SCHEMBL7943207

SCHEMBL7943207

CCC(Cc1ccc(OC)c(OC)c1)(C(=O)c1ccccc1)N(C)C.CCC(Cc1ccc(OC)cc1)(C(=O)c1ccccc1)N(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.47
HTT P42858 3/20 0.47
NPC1 O15118 2/20 0.47
MAPT P10636 4/20 0.44
ALDH1A1 P00352 3/20 0.44
GLA P06280 1/20 0.44
ACHE P22303 5/20 0.43
BCHE P06276 3/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
TAS2R14 Q9NYV8 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.42
TP53 P04637 1/20 0.42
HPGD P15428 1/20 0.42
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4652464 0.94 ACHE (0.47) HTTALDH1A1ACHEBCHEMEN1
SCHEMBL4651502 0.91 ACHE (0.48) NPC1MAPTALDH1A1ACHEMEN1
SCHEMBL4651504 0.86 ACHE (0.51) HTTNPC1MAPTALDH1A1ACHE
SCHEMBL8631398 0.85 ACHE (0.43) NPC1MAPTALDH1A1ACHEMEN1
SCHEMBL29421022 0.85 ACHE (0.53) LMNAHTTNPC1MAPTALDH1A1
SCHEMBL480430 0.85 ACHE (0.53) LMNAHTTNPC1MAPTALDH1A1
SCHEMBL8897587 0.81 ACHE (0.57) HTTNPC1MAPTALDH1A1ACHE
SCHEMBL5590415 0.80 L3MBTL1 (0.45) HTTNPC1MAPTALDH1A1ACHE
SCHEMBL9316355 0.80 CTNNB1 (0.50) LMNAMAPTALDH1A1ACHEBCHE
SCHEMBL4650526 0.79 RIPK1 (0.43) LMNANPC1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242057-B1 GENERATING PHOTOINITIATORS KIMBERLY-CLARK WORLDWIDE, INC. 2001-06-05 US disclosed
US-6008268-A A PHOTOREACTOR COMPOUND COMPRISING A WAVELENGTH-SPECIFIC SENSITIZER MOIETY COVALENTLY BONDED TO TWO REACTIVE SPECIES-GENERATING PHOTOINITIATOR MOIETIES; PHOTOPOLYMERIZATION; PHOTOCURING; LOW-ENERGY LAMPS KIMBERLY-CLARK WORLDWIDE, INC. (US) 1999-12-28 US disclosed
US-5811199-A Adhesive compositions containing a photoreactor composition KIMBERLY-CLARK WORLDWIDE, INC. (US) 1998-09-22 US disclosed
US-5798015-A Method of laminating a structure with adhesive containing a photoreactor composition KIMBERLY-CLARK WORLDWIDE, INC. (US) 1998-08-25 US disclosed
US-5739175-A Photoreactor composition containing an arylketoalkene wavelength-specific sensitizer KIMBERLY-CLARK WORLDWIDE, INC. (US) 1998-04-14 US disclosed