SCHEMBL4652787

SCHEMBL4652787

C=CCC1=Cc2cc(CCCCC)c(CCCCC)cc2[CH]1

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.33
MEN1 O00255 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
ALOX5 P09917 1/20 0.32
MAPT P10636 1/20 0.32
TYR P14679 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
THRA P10827 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4654015 0.81 PTGS2 (0.35) MEN1CYP3A4KMT2ATHRATHRB
SCHEMBL3278368 0.81 DHFR (0.31)
SCHEMBL6525334 0.80 LIPG (0.39) LIPGALOX5MAPTALOX15THRA
SCHEMBL4653119 0.79 GABRA1 (0.34)
SCHEMBL4649970 0.79 TYR (0.33) LIPGMEN1TP53CYP3A4ALOX5
SCHEMBL10682962 0.67 ALOX5 (0.50) MEN1TP53CYP3A4ALOX5MAPT
SCHEMBL18889039 0.66 ALOX5 (0.50) LIPGMEN1TP53CYP3A4ALOX5
SCHEMBL88563 0.66 LIPG (0.50) LIPGCYP3A4ALOX5THRATHRB
SCHEMBL4787984 0.65 LIPG (0.53) LIPGALOX5THRATHRB
Ammonia Solution, Strong SCHEMBL28810899 0.65 LIPG (0.49) LIPGCYP3A4ALOX5THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1188763-B1 Metallocenes and their use in olefin polymerisation BASELL POLYOLEFINE GMBH (DE) 2005-03-09 EP claimed
EP-1188763-A2 Metallocenes and their use in olefin polymerisation Basell Polyolefine GmbH (DE) 2002-03-20 EP claimed
EP-0906932-B1 Film and stretch packaging film DENKI KAGAKU KOGYO KK (JP) 2008-07-02 EP disclosed
EP-1188763-B1 Metallocenes and their use in olefin polymerisation BASELL POLYOLEFINE GMBH (DE) 2005-03-09 EP disclosed
US-6472490-B1 AN ETHYLENE-AROMATIC VINYL COMPOUND COPOLYMER HAVING AN AROMATIC VINYL COMPOUND CONTENT OF FROM 1 TO LESS THAN 55% BY MOLAR FRACTION, WHICH HAS A HAZE OF AT MOST 41.5% WHEN MOLDED; METHINE DYES DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2002-10-29 US disclosed
US-6417308-B2 A HOMO- OR COPOLYMER OF AN ALPHA-OLEFIN WITH AN AROMATIC VINYL COMPOUND OF AN ALTERNATING, HIGHLY ISOTACTIC STRUCTURE WITH HEAD-TO TAIL CHAINS OF AT LEAST TWO AROMATIC VINYLS; FOOD PACKAGING; SELF-ADHESIVE; STRENGTH DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2002-07-09 US disclosed
EP-0659756-B1 Metallocenes BASELL POLYOLEFINE GMBH (DE) 2002-04-03 EP disclosed
EP-0659757-B1 Metallocenes BASELL POLYOLEFINE GMBH (DE) 2002-03-27 EP disclosed
EP-1188763-A2 Metallocenes and their use in olefin polymerisation Basell Polyolefine GmbH (DE) 2002-03-20 EP disclosed
US-6348556-B1 COORDINATION CATALYST OF TRANSITION METAL COMPLEX CONTAINING INDENYL GROUP(S) AND COCATALYST; ISOTACTIC; CATALYSIS, ADDITION COPOLYMERIZATION DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2002-02-19 US disclosed
CN-1075819-C Metallocen method for preparation of same and application of same as catalyst HOECHST AG (DE) 2001-12-05 CN disclosed
US-5576260-A POLYMERIZATION CATALYSTS FOR OLEFINS HOECHST AKTIENGESELLSCHAFT (DE) 1996-11-19 US disclosed
US-5543373-A OLEFIN POLYMERIZATION CATALYST HOECHST AG (DE) 1996-08-06 US disclosed
US-5532396-A HAS TWO INDENYL LIGANDS WITH DIFFERENT SUBSTITUTION PATTERNS ON THE SIX-MEMBERED RINGS. LIGANDS ARE JOINED BY DIVALENT GROUP CONNECTING FIVE-MEMBERED RINGS. METAL IS FROM GROUP /IVB/, /VB/ OR /VIB/. OLEFIN POLYMERIZATION CATALYST HOECHST AKTIENGESELLSCHAFT (DE) 1996-07-02 US disclosed
CN-1109061-A Metallocenic compound HOECHST AG (DE) 1995-09-27 CN disclosed
CN-1107854-A Metalocenes compound HOECHST AG (DE) 1995-09-06 CN disclosed
CN-1107162-A Metallocen method for preparation of same and application of same as catalyst HOECHST AG (DE) 1995-08-23 CN disclosed
EP-0659756-A1 Metallocenes HOECHST AKTIENGESELLSCHAFT (DE) 1995-06-28 EP disclosed
EP-0659757-A1 Metallocenes HOECHST AKTIENGESELLSCHAFT (DE) 1995-06-28 EP disclosed
EP-0654476-A1 Metallocenes, their preparation and use as catalysts HOECHST AKTIENGESELLSCHAFT (DE) 1995-05-24 EP disclosed