SCHEMBL4652973

SCHEMBL4652973

CCN(CC)c1c(O)ccc(N)c1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100B P04271 1/20 0.43
ESR1 P03372 3/20 0.39
ESR2 Q92731 2/20 0.39
AR P10275 1/20 0.39
PRKCI P41743 1/20 0.38
ACHE P22303 1/20 0.37
ALDH1A1 P00352 6/20 0.36
CYP3A4 P08684 3/20 0.36
ALOX15 P16050 2/20 0.36
HSD17B10 Q99714 2/20 0.36
TSHR P16473 2/20 0.36
MAPK1 P28482 2/20 0.36
RECQL P46063 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
PSMD14 O00487 1/20 0.36
GFER P55789 1/20 0.36
GAA P10253 2/20 0.33
USP2 O75604 1/20 0.33
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8586253 0.85 S100B (0.43) S100BESR1ESR2ARPRKCI
SCHEMBL4636717 0.84 S100B (0.48) S100BALDH1A1CYP3A4ALOX15TSHR
SCHEMBL27983245 0.80 ALDH1A1 (0.39) S100BESR1ESR2ARPRKCI
SCHEMBL10586581 0.78 S100B (0.40) S100BESR1ESR2ARPRKCI
SCHEMBL7534253 0.78 ALDH1A1 (0.40) ESR1ESR2ARALDH1A1CYP3A4
SCHEMBL8586252 0.73 S100B (0.47) S100BESR1ESR2ARPRKCI
SCHEMBL30816668 0.70 ALDH1A1 (0.48) ALDH1A1CYP3A4ALOX15HSD17B10TSHR
SCHEMBL525507 0.69 ALDH1A1 (0.48) ESR1ESR2ARALDH1A1CYP3A4
SCHEMBL3117753 0.68 TRPA1 (0.46) ESR1ALDH1A1CYP3A4HSD17B10MAPK1
SCHEMBL6472907 0.68 CYP3A4 (0.52) S100BESR1ALDH1A1CYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1747046-B1 USE OF SPECIALLY FORMYLATED QUINOLINIUM DERIVATIVES IN COMBINATION WITH AMINO-SUBSTITUTED PYRIMIDINE DERIVATIVES AND AT LEAST ONE ADDITIONAL PRIMARY OR SECONDARY, AROMATIC AMINE HENKEL AG & CO KGAA (DE) 2008-09-24 EP claimed
EP-1311231-B1 AGENT FOR COLOURING KERATIN-CONTAINING FIBRES COMPRISING AT LEAST ONE OXOCYCLOPENTENE DERIVATIVE HENKEL KGAA (DE) 2006-11-22 EP claimed
EP-1194116-B1 AGENT FOR DYEING FIBRES CONTAINING KERATIN HENKEL KGAA (DE) 2005-05-04 EP claimed
CN-1708476-A Novel amide compounds having MCH-antagonistic action and medicaments comprising these compounds BOEHRINGER INGELHEIM PHARMA (DE) 2005-12-14 CN disclosed
EP-1432428-A1 Agent for colouring fibres containing keratin Henkel Kommanditgesellschaft auf Aktien (DE) 2004-06-30 EP disclosed
WO-2003030842-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO disclosed