SCHEMBL8586252

SCHEMBL8586252

CCN(CC)c1c(N)ccc(C)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100B P04271 1/20 0.47
ALDH1A1 P00352 7/20 0.36
CYP3A4 P08684 3/20 0.36
TSHR P16473 3/20 0.36
TDP1 Q9NUW8 3/20 0.36
PSMD14 O00487 1/20 0.36
MAPK1 P28482 1/20 0.36
RECQL P46063 1/20 0.36
GFER P55789 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ESR1 P03372 2/20 0.35
AR P10275 1/20 0.35
ESR2 Q92731 1/20 0.35
MAPT P10636 2/20 0.34
RAB9A P51151 1/20 0.34
CASP1 P29466 2/20 0.32
GAA P10253 2/20 0.32
PKM P14618 1/20 0.32
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10586581 0.82 S100B (0.40) S100BALDH1A1CYP3A4TSHRTDP1
SCHEMBL8586253 0.77 S100B (0.43) S100BALDH1A1CYP3A4TSHRTDP1
SCHEMBL4636717 0.75 S100B (0.48) S100BALDH1A1CYP3A4TSHRTDP1
SCHEMBL4652973 0.73 S100B (0.43) S100BALDH1A1CYP3A4TSHRTDP1
SCHEMBL27588271 0.73 S100B (0.47) S100BALDH1A1CYP3A4TSHRTDP1
SCHEMBL5514568 0.72 CD44 (0.46) S100BALDH1A1CYP3A4TSHRTDP1
SCHEMBL11884085 0.71 S100B (0.41) S100BALDH1A1CYP3A4TSHRTDP1
SCHEMBL7655945 0.70 ALDH1A1 (0.44) S100BALDH1A1CYP3A4TSHRTDP1
SCHEMBL9417107 0.69 ALDH1A1 (0.40) S100BALDH1A1CYP3A4TSHRTDP1
SCHEMBL5356606 0.69 NOS3 (0.39) S100BALDH1A1CYP3A4TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0803063-A4 METHODS FOR PRODUCTION OF LARGE CATALOGUED CHEMICAL LIBRARIES PANLABS INC (US) 1998-04-29 EP disclosed
EP-0803063-A1 METHODS FOR PRODUCTION OF LARGE CATALOGUED CHEMICAL LIBRARIES PANLABS INCORPORATED (US) 1997-10-29 EP disclosed
WO-1996021859-A1 METHODS FOR PRODUCTION OF LARGE CATALOGUED CHEMICAL LIBRARIES PANLABS, INC. (US) 1996-07-18 WO disclosed