Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.30 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.30 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1263541 | 0.83 | THRB (0.47) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL6556703 | 0.81 | TSHR (0.49) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL4653334 | 0.81 | THRB (0.36) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL28013558 | 0.80 | CSNK2A1 (0.40) | THRBTSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL29445300 | 0.78 | TP53 (0.49) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL18424772 | 0.76 | PTPN1 (0.43) | THRBTSHRALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL12386663 | 0.76 | TSHR (0.50) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL10892751 | 0.76 | TSHR (0.50) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL10890546 | 0.76 | TSHR (0.50) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL28531604 | 0.76 | THRB (0.43) | THRBALDH1A1TP53CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986588-A2 | SELF ETCH ALL PURPOSE DENTAL COMPOSITION | Pentron Clinical Technologies, LLC (US) | 2008-11-05 | — | — | EP | claimed |
| US-20080242761-A1 | One part acrylated monomer with aromatic carboxylic anhydride functionality, multifunctional acrylate resin, diluent monomer and curing system; one step restorative dentistry; self and light curable | JIA WEITAO | 2008-10-02 | — | — | US | claimed |
| WO-2007100569-A2 | SELF ETCH ALL PURPOSE DENTAL COMPOSITION | PENTRON CLINICAL TECHNOLOGIES LLC (US) | 2007-09-07 | — | — | WO | claimed |
| US-20070197683-A1 | SELF ETCH ALL PURPOSE DENTAL COMPOSITIONS, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF | PENTRON CLINICAL TECHNOLOGIES, INC (US) | 2007-08-23 | — | — | US | claimed |
| US-20070197682-A1 | Self etch all purpose dental cement composition, method of manufacture, and method of use thereof | PENTRON CORPORATION | 2007-08-23 | — | — | US | claimed |
| EP-0843184-B1 | Ocular lens material | MENICON CO LTD (JP) | 2004-03-03 | — | — | EP | disclosed |
| EP-0947856-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1999-10-06 | — | — | EP | disclosed |
| US-5811502-A | CONTAINING COPOLYMERS OF METHACRYLIC ESTERS AND HAVING OXYGEN PERMEABILITY, SUFFICIENT HARDNESS AND WETTABILITY | MENICON CO., LTD. (JP) | 1998-09-22 | — | — | US | disclosed |
| EP-0843184-A2 | Ocular lens material | Menicon Co., Ltd. (JP) | 1998-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197682-A1 | Self etch all purpose dental cement composition, method of manufacture, and method of use thereof | FHIT, COPE, ASH2L | THRB 3947/4885TSHR 4848/4885ALDH1A1 4447/4885 |
| US-20070197683-A1 | SELF ETCH ALL PURPOSE DENTAL COMPOSITIONS, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF | CAD, FHIT, ACR | THRB 1851/4885TSHR 4432/4885ALDH1A1 681/4885 |
| US-20080242761-A1 | One part acrylated monomer with aromatic carboxylic anhydride functionality, multifunctional acrylate resin, diluent monomer and curing system; one step restorative dentistry; self and light curable | CAD, TAS2R42, ACR | THRB 1701/4885TSHR 3760/4885ALDH1A1 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.