Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4653328 | 0.77 | KIF11 (0.35) | TSHRKIF11 | |
| SCHEMBL8572359 | 0.74 | TSHR (0.37) | TSHRKIF11CYP1A2 | |
| SCHEMBL8077580 | 0.72 | KIF11 (0.38) | TSHRKIF11MAPK1KCNN4ALDH1A1 | |
| SCHEMBL4367368 | 0.71 | MAPK1 (0.42) | TSHRKIF11MAPK1KCNN4ALDH1A1 | |
| SCHEMBL16062155 | 0.68 | ALDH1A1 (0.41) | KIF11MAPK1KCNN4ALDH1A1CYP1A2 | |
| SCHEMBL8572747 | 0.68 | ALDH1A1 (0.39) | TSHRKIF11MAPK1KCNN4ALDH1A1 | |
| SCHEMBL8813285 | 0.68 | MAPK1 (0.39) | TSHRKIF11MAPK1KCNN4ALDH1A1 | |
| SCHEMBL6074049 | 0.67 | TSHR (0.48) | TSHRKIF11MAPK1KCNN4ALDH1A1 | |
| SCHEMBL8973 | 0.66 | KIF11 (0.48) | TSHRKIF11MAPK1KCNN4ALDH1A1 | |
| SCHEMBL297786 | 0.66 | MAPK1 (0.52) | TSHRKIF11MAPK1KCNN4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713836-B1 | PREPARATION METHOD OF POLYMERISATION CATALYST FOR PRODUCTION OF POLYETHYLENE WITH BROAD MOLECULAR WEIGHT DISTRIBUTION | HANWHA CHEMICAL CORP (KR) | 2014-12-24 | — | — | EP | claimed |
| EP-1539838-B1 | COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE SRL (IT) | 2009-11-25 | — | — | EP | claimed |
| EP-1302480-B1 | Catalyst percursor for homo-or copolymerization of olefins and polymerization process using that catalyst precursor | SAUDI BASIC IND CORP SABIC (SA) | 2004-08-11 | — | — | EP | claimed |