SCHEMBL465401

SCHEMBL465401

CCO[Si](OCC)(OCC)c1cccc(SSc2cccc([Si](OCC)(OCC)OCC)c2)c1

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.32
HSD17B10 Q99714 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
HSP90AA1 P07900 1/20 0.32
MAPT P10636 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
MGLL Q99685 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL574271 0.84 TP53 (0.33) CYP1A2
SCHEMBL6561373 0.77 ACHE (0.42) HPGDCYP1A2CYP2C9MAPTSMN1; SMN2
SCHEMBL28532235 0.76 ALDH1A1 (0.41) HSD17B10CYP2C9SMN1; SMN2
SCHEMBL434177 0.76 CYP3A4 (0.48) MAPTSMN1; SMN2
SCHEMBL3675040 0.76 GABRG2 (0.43) HPGDMAPTSMN1; SMN2
SCHEMBL15735907 0.76 ACHE (0.39) MAPTSMN1; SMN2
SCHEMBL30022263 0.76 CYP3A4 (0.48) MAPTSMN1; SMN2
SCHEMBL2329175 0.76 CYP3A4 (0.36) MAPT
SCHEMBL13027214 0.74 ACHE (0.44) HPGDHSD17B10MAPT
SCHEMBL29662856 0.74 ACHE (0.44) HPGDHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2829543-B1 SILATED CORE POLYSULFIDES, THEIR PREPARATION AND USE IN FILLED ELASTOMER COMPOSITIONS MOMENTIVE PERFORMANCE MAT INC (US) 2021-06-09 EP claimed
EP-2829544-A1 Silated cyclic core polysulfides, their preparation and use in filled elastomer compositions Momentive Performance Materials Inc. (US) 2015-01-28 EP claimed
US-8501849-B2 Silated core polysulfides, their preparation and use in filled elastomer compositions MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-08-06 US claimed
US-20120225984-A1 SILATED CORE POLYSULFIDES, THEIR PREPARATION AND USE IN FILLED ELASTOMER COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-09-06 US claimed
US-8188174-B2 Silated core polysulfides, their preparation and use in filled elastomer compositions MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-05-29 US claimed
US-7968636-B2 bis-(3-triethoxysilylpropyl) disulfide, bis-(3-triethoxysilylpropyl)tetrasulfide and 1,2,4-tris(6-triethoxysilyl-3,4-dithiaheptyl)cyclohexanel; vulcanizable rubber such as natural rubbers, synthetic polyisoprene, polyisobutylene, polybutadiene, and random styrene-butadiene copolymer; an active filler CONTINENTAL AG (DE) 2011-06-28 US claimed
US-7968634-B2 bis-(3-triethoxysilylpropyl) disulfide, bis-(3-triethoxysilylpropyl)tetrasulfide and 1,2,4-tris(6-triethoxysilyl-3,4-dithiaheptyl)cyclohexanel; vulcanizable rubber such as natural rubbers, synthetic polyisoprene, polyisobutylene, polybutadiene, and random styrene-butadiene copolymer; an active filler CONTINENTAL AG (DE) 2011-06-28 US claimed
US-7687558-B2 Silated cyclic core polysulfides, their preparation and use in filled elastomer compositions MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-03-30 US claimed
EP-2114961-A1 SILATED CORE POLYSULFIDES, THEIR PREPARATION AND USE IN FILLED ELASTOMER COMPOSITIONS Momentive Performance Materials Inc. (US) 2009-11-11 EP claimed
EP-2114962-A1 SILATED CYCLIC CORE POLYSULFIDES, THEIR PREPARATION AND USE IN FILLED ELASTOMER COMPOSTIONS Momentive Performance Materials Inc. (US) 2009-11-11 EP claimed
EP-2099858-A1 TIRE COMPOSITIONS AND COMPONENTS CONTAINING SILATED CYCLIC CORE POLYSULFIDES Continental Aktiengesellschaft (DE) 2009-09-16 EP claimed
EP-2099860-A1 TIRE COMPOSITIONS AND COMPONENTS CONTAINING SILATED CORE POLYSULFIDES Continental AG (DE) 2009-09-16 EP claimed
WO-2008085453-A1 SILATED CORE POLYSULFIDES, THEIR PREPARATION AND USE IN FILLED ELASTOMER COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-07-17 WO claimed
WO-2008085455-A1 SILATED CYCLIC CORE POLYSULFIDES, THEIR PREPARATION AND USE IN FILLED ELASTOMER COMPOSTIONS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-07-17 WO claimed
WO-2008083244-A1 TIRE COMPOSITIONS AND COMPONENTS CONTAINING SILATED CORE POLYSULFIDES CONTINENTAL AG (DE) 2008-07-10 WO claimed
WO-2008083242-A1 TIRE COMPOSITIONS AND COMPONENTS CONTAINING SILATED CYCLIC CORE POLYSULFIDES CONTINENTAL AG (DE) 2008-07-10 WO claimed
US-20080161462-A1 TIRE COMPOSITIONS AND COMPONENTS CONTAINING SILATED CYCLIC CORE POLYSULFIDES CONTINENTAL AG (DE) 2008-07-03 US claimed
US-20080161452-A1 TIRE COMPOSITIONS AND COMPONENTS CONTAINING SILATED CORE POLYSULFIDES CONTINENTAL AG (DE) 2008-07-03 US claimed
US-20080161477-A1 Silated core polysulfides, their preparation and use in filled elastomer compositions MOMENTIVE PERFORMANCE MATERIALS INC. 2008-07-03 US claimed
US-20080161459-A1 Silated cyclic core polysulfides, their preparation and use in filled elastomer compositions MOMENTIVE PERFORMANCE MATERIALS INC. 2008-07-03 US claimed