Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 17/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.42 |
| ▸ | F11 | P03951 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551027 | 0.89 | GPR119 (0.49) | S1PR1TBK1 | |
| SCHEMBL5133256 | 0.81 | USP30 (0.41) | S1PR1TBK1 | |
| SCHEMBL4414174 | 0.78 | GPR119 (0.49) | TBK1 | |
| SCHEMBL14640963 | 0.76 | ROCK2 (0.45) | S1PR1TBK1 | |
| SCHEMBL13602311 | 0.76 | GPR119 (0.51) | SMPD1 | |
| SCHEMBL4416009 | 0.76 | CHRM2 (0.37) | S1PR1SMPD1 | |
| SCHEMBL4412893 | 0.75 | SPHK1 (0.47) | — | |
| SCHEMBL4414082 | 0.74 | KCNH2 (0.39) | S1PR1SMPD1 | |
| SCHEMBL4424803 | 0.74 | SPHK1 (0.46) | S1PR1SMPD1 | |
| SCHEMBL4422335 | 0.73 | PTGS2 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1907383-A1 | GPCR AGONISTS | Prosidion Limited (GB) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007003960-A1 | GPCR AGONISTS | PROSIDION LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |