Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 10/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3923958 | 0.75 | LMNA (0.40) | ALDH1A1HTTCA2LMNAMAPK1 | |
| SCHEMBL2618496 | 0.64 | ALDH1A1 (0.50) | ALDH1A1HTTLMNAMAPK1HPGD | |
| SCHEMBL22508643 | 0.63 | ALDH1A1 (0.41) | ALDH1A1HTTLMNAMAPK1HPGD | |
| SCHEMBL15220314 | 0.60 | FBP1 (0.40) | FBP1CREBBP | |
| SCHEMBL16024140 | 0.59 | FBP1 (0.34) | FBP1CREBBP | |
| SCHEMBL4789468 | 0.59 | CA2 (0.46) | CA2 | |
| SCHEMBL6568298 | 0.57 | MAPK1 (0.64) | ALDH1A1HTTCA2LMNAMAPK1 | |
| SCHEMBL266769 | 0.56 | KDM1A (0.39) | ALDH1A1HTTMAPK1HPGD | |
| SCHEMBL28283415 | 0.54 | TSHR (0.47) | ALDH1A1CA2LMNAMAPK1HPGD | |
| SCHEMBL12269650 | 0.53 | PDE10A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996588-A1 | NOVEL DUAL ACTION RECEPTORS ANTAGONISTS (DARA) AT THE ATI AND ETA RECEPTORS | Torrent Pharmaceuticals Ltd (IN) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007100295-A1 | NOVEL DUAL ACTION RECEPTORS ANTAGONISTS (DARA) AT THE ATI AND ETA RECEPTORS | TORRENT PHARMACEUTICALS LTD (IN) | 2007-09-07 | — | — | WO | disclosed |