Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.30 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
| ▸ | ACACA | Q13085 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL309857 | 0.79 | HPGD (0.45) | SMN1; SMN2ALDH1A1ACACBACACA | |
| SCHEMBL4658596 | 0.78 | CHRM2 (0.33) | HRH3 | |
| SCHEMBL4716959 | 0.78 | DRD2 (0.38) | — | |
| SCHEMBL16673574 | 0.77 | SIGMAR1 (0.38) | HRH3 | |
| SCHEMBL16341947 | 0.74 | CHRM1 (0.34) | — | |
| SCHEMBL4046200 | 0.74 | L3MBTL3 (0.33) | SMN1; SMN2 | |
| SCHEMBL4720598 | 0.74 | TP53 (0.37) | SMN1; SMN2ALDH1A1HRH3 | |
| SCHEMBL4067285 | 0.72 | CHRM2 (0.36) | HRH3 | |
| SCHEMBL4717872 | 0.72 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL249745 | 0.71 | DRD2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009071691-A2 | OXINDOLE DERIVATIVES AND THE USE THEREOF AS A MEDICATION | ABBOTT GMBH & CO. KG (DE) | 2009-06-11 | — | — | WO | disclosed |