Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.31 |
| ▸ | HTR3B | O95264 | 2/20 | 0.31 |
| ▸ | HTR3A | P46098 | 2/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4660687 | 1.00 | IDO1 (0.34) | IDO1TSHRTRPA1HTR3EHTR3B | |
| SCHEMBL4660608 | 0.89 | DAO (0.35) | TRPA1 | |
| SCHEMBL4660671 | 0.81 | HTR3E (0.51) | IDO1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL4660711 | 0.81 | FFAR4 (0.40) | — | |
| SCHEMBL4764526 | 0.76 | PIK3CA (0.47) | TSHRTRPA1ITGB3ITGAV | |
| SCHEMBL4660728 | 0.75 | TRPA1 (0.39) | TRPA1 | |
| SCHEMBL1294403 | 0.72 | AOC2 (0.40) | IDO1TSHRHTR3EHTR3BHTR3A | |
| SCHEMBL4659392 | 0.72 | MAOA (0.44) | TRPA1 | |
| SCHEMBL1295302 | 0.72 | AOC2 (0.40) | IDO1TSHRHTR3EHTR3BHTR3A | |
| SCHEMBL1294399 | 0.72 | AOC2 (0.40) | IDO1TSHRHTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004166-A2 | INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT AND PREVENTION OF DISEASES | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2008-12-24 | — | — | EP | claimed |
| WO-2007120528-A2 | INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT AND PREVENTION OF DISEASES | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2007-10-25 | — | — | WO | claimed |