Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4659392 | 0.80 | MAOA (0.44) | TRPA1MAOBRIPK1 | |
| SCHEMBL4659366 | 0.75 | IDO1 (0.34) | TRPA1 | |
| SCHEMBL4660687 | 0.75 | IDO1 (0.34) | TRPA1 | |
| SCHEMBL4660558 | 0.75 | RIPK1 (0.41) | TRPA1RIPK1CES2CES1 | |
| SCHEMBL5511607 | 0.74 | MAOB (0.46) | TRPA1MAOBRIPK1CES2CES1 | |
| SCHEMBL4660608 | 0.73 | DAO (0.35) | TRPA1 | |
| SCHEMBL4659363 | 0.73 | SIGMAR1 (0.41) | MAOB | |
| SCHEMBL1294638 | 0.72 | AOC2 (0.43) | MAOBCES2CES1 | |
| SCHEMBL1294635 | 0.72 | AOC2 (0.43) | MAOBCES2CES1 | |
| SCHEMBL1296000 | 0.72 | AOC2 (0.43) | MAOBCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004166-A2 | INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT AND PREVENTION OF DISEASES | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2008-12-24 | — | — | EP | claimed |
| WO-2007120528-A2 | INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT AND PREVENTION OF DISEASES | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2007-10-25 | — | — | WO | claimed |