Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | VNN1 | O95497 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582402 | 0.84 | CES1 (0.52) | L3MBTL1TDP1HPGDKMT2AMEN1 | |
| SCHEMBL7965958 | 0.83 | RAB9A (0.51) | TDP1KMT2ASMN1; SMN2CTBP2RAB9A | |
| SCHEMBL4659306 | 0.83 | KMT2A (0.50) | L3MBTL1TDP1HPGDKMT2AMEN1 | |
| SCHEMBL4660490 | 0.82 | HTT (0.57) | KMT2ASMN1; SMN2CTBP2RAB9ANPC1 | |
| SCHEMBL4768501 | 0.82 | NR1H4 (0.54) | SMN1; SMN2RAB9ALMNAALDH1A1MAPT | |
| SCHEMBL4940818 | 0.81 | L3MBTL1 (0.62) | L3MBTL1TDP1HPGDKMT2AMEN1 | |
| SCHEMBL7114566 | 0.80 | L3MBTL1 (0.58) | L3MBTL1TDP1HPGDKMT2AMEN1 | |
| SCHEMBL4659414 | 0.79 | CTBP2 (0.54) | L3MBTL1HPGDKMT2AMEN1CTBP2 | |
| SCHEMBL1294752 | 0.79 | TDP1 (0.46) | L3MBTL1TDP1HPGDKMT2AMEN1 | |
| SCHEMBL11219229 | 0.78 | L3MBTL1 (0.76) | L3MBTL1TDP1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004166-A2 | INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT AND PREVENTION OF DISEASES | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007120528-A2 | INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT AND PREVENTION OF DISEASES | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2007-10-25 | — | — | WO | disclosed |