Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.44 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4659431 | 0.83 | L3MBTL1 (0.54) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL4582402 | 0.82 | CES1 (0.52) | KMT2AMEN1ALDH1A1RAB9ACYP2C9 | |
| SCHEMBL7965958 | 0.81 | RAB9A (0.51) | KMT2AALDH1A1NPC1RAB9ACTBP2 | |
| SCHEMBL4662034 | 0.81 | TACR1 (0.40) | KMT2AMEN1ALDH1A1RAB9ACTBP2 | |
| SCHEMBL1479915 | 0.80 | NPC1 (0.55) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL4327956 | 0.79 | CTBP2 (0.52) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL4660490 | 0.77 | HTT (0.57) | KMT2AALDH1A1NPC1RAB9ACTBP2 | |
| SCHEMBL28297938 | 0.77 | KMT2A (0.49) | KMT2AMEN1ALDH1A1RAB9ACYP2C9 | |
| SCHEMBL4768501 | 0.77 | NR1H4 (0.54) | ALDH1A1RAB9ALMNAMAPT | |
| SCHEMBL8406795 | 0.76 | L3MBTL1 (0.66) | KMT2AMEN1ALDH1A1CTBP2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004166-A2 | INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT AND PREVENTION OF DISEASES | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007120528-A2 | INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT AND PREVENTION OF DISEASES | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2007-10-25 | — | — | WO | disclosed |