SCHEMBL46600

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24101723	0.92	KIT (0.48)	DDB1CRBNPOLBKITMAPT
	SCHEMBL30339672	0.92	KIT (0.48)	DDB1CRBNPOLBKITMAPT
	SCHEMBL24914388	0.87	DDB1 (0.52)	DDB1CRBNPOLBKITMAPT
	SCHEMBL20353893	0.83	LMNA (0.51)	TRPV1FAAHMAPTCDK4CCND1
	SCHEMBL350201	0.81	TRPV1 (0.69)	TRPV1FAAHMAPTCDK4CCND1
	SCHEMBL2270578	0.81	PARP1 (0.57)	TRPV1FAAHMAPK1PARP1TNKS2
	SCHEMBL20348528	0.81	CDK4 (0.47)	TRPV1FAAHCDK4CCND1
	SCHEMBL21588363	0.81	CDK9 (0.44)	TRPV1KITMAPTF12ESR2
	SCHEMBL30667649	0.80	MAPT (0.46)	TRPV1FAAHMAPTCDK4CCND1
	SCHEMBL29826209	0.79	TRPV1 (0.49)	TRPV1FAAHMAPK1PARP1TNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.