Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4660128 | 0.91 | ACP3 (0.42) | PPARGPPARAALDH1A1CTSSCTSK | |
| SCHEMBL4661436 | 0.89 | MEN1 (0.36) | PPARGPPARAALDH1A1CTSSCTSK | |
| SCHEMBL4662672 | 0.88 | MAPT (0.43) | PPARGPPARAALDH1A1CTSSCTSK | |
| SCHEMBL4661534 | 0.87 | CMA1 (0.39) | PPARGPPARAALDH1A1MGAMGAA | |
| SCHEMBL4662654 | 0.86 | PPARG (0.38) | PPARGPPARAALDH1A1CTSSCTSK | |
| SCHEMBL4661396 | 0.83 | PPARG (0.38) | PPARGPPARAALDH1A1CTSSCTSK | |
| SCHEMBL4661453 | 0.81 | MEN1 (0.45) | PPARGPPARACYP2C9CYP2C19MEN1 | |
| SCHEMBL4661587 | 0.81 | ESR1 (0.45) | PPARGPPARAALDH1A1CTSSCTSK | |
| SCHEMBL4661407 | 0.81 | PPARG (0.46) | PPARGPPARACTSSCTSKHTT | |
| SCHEMBL4660153 | 0.81 | PPARG (0.36) | PPARGPPARAALDH1A1CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620102-B1 | 3-(1-NAPHTHYL)-2-CYANOPROPANOIC ACID DERIVATIVES AS ESTROGEN RECEPTOR LIGANDS | WYETH CORP (US) | 2008-12-24 | — | — | EP | claimed |