Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4660186 | 0.88 | PPARG (0.37) | MAPTALDH1A1GAAOPRM1OPRD1 | |
| SCHEMBL4660128 | 0.88 | ACP3 (0.42) | ALDH1A1L3MBTL1HPGDSMN1; SMN2PPARG | |
| SCHEMBL4661436 | 0.86 | MEN1 (0.36) | MAPTALDH1A1OPRM1OPRD1KDM4E | |
| SCHEMBL4661534 | 0.84 | CMA1 (0.39) | ALDH1A1GAAHPGDPPARGPPARA | |
| SCHEMBL4661396 | 0.81 | PPARG (0.38) | ALDH1A1GAAHPGDLMNAPPARG | |
| SCHEMBL4662654 | 0.81 | PPARG (0.38) | ALDH1A1POLBHPGDPPARGPPARA | |
| SCHEMBL4661453 | 0.79 | MEN1 (0.45) | MAPTPOLBL3MBTL1KDM4EMEN1 | |
| SCHEMBL4661587 | 0.79 | ESR1 (0.45) | ALDH1A1TDP1GAAPOLBL3MBTL1 | |
| SCHEMBL4661407 | 0.79 | PPARG (0.46) | HPGDPPARGPPARACTSSCTSK | |
| SCHEMBL4660153 | 0.78 | PPARG (0.36) | MAPTALDH1A1GAAHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620102-B1 | 3-(1-NAPHTHYL)-2-CYANOPROPANOIC ACID DERIVATIVES AS ESTROGEN RECEPTOR LIGANDS | WYETH CORP (US) | 2008-12-24 | — | — | EP | claimed |