Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.46 |
| ▸ | PPARA | Q07869 | 10/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4660128 | 0.86 | ACP3 (0.42) | PPARGPPARACYP2C9CYP2C19CYP1A2 | |
| SCHEMBL4661396 | 0.86 | PPARG (0.38) | PPARGPPARACYP2C9CYP2C19CYP1A2 | |
| SCHEMBL4662654 | 0.86 | PPARG (0.38) | PPARGPPARACYP2C9CYP2C19CYP1A2 | |
| SCHEMBL4661587 | 0.84 | ESR1 (0.45) | PPARGPPARACTSSCTSKHPGD | |
| SCHEMBL4660153 | 0.83 | PPARG (0.36) | PPARGPPARACYP2C9CYP2C19CYP1A2 | |
| SCHEMBL4660186 | 0.81 | PPARG (0.37) | PPARGPPARACYP2C9CYP2C19ACP3 | |
| SCHEMBL4661474 | 0.81 | ALDH1A1 (0.42) | PPARGPPARACYP1A2 | |
| SCHEMBL4661534 | 0.81 | CMA1 (0.39) | PPARGPPARACYP2C9CYP2C19ACP3 | |
| SCHEMBL4660080 | 0.80 | ESR1 (0.42) | PPARGPPARAHPGDHTT | |
| SCHEMBL4661436 | 0.80 | MEN1 (0.36) | PPARGPPARACYP2C9CYP2C19CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620102-B1 | 3-(1-NAPHTHYL)-2-CYANOPROPANOIC ACID DERIVATIVES AS ESTROGEN RECEPTOR LIGANDS | WYETH CORP (US) | 2008-12-24 | — | — | EP | claimed |