Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SRC | P12931 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | VNN1 | O95497 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6606077 | 0.83 | KMT2A (0.42) | RAB9ASRCPOLBTP53ALDH1A1 | |
| SCHEMBL6864466 | 0.82 | TAAR1 (0.50) | RAB9ASRCVNN1TAAR1MAPK1 | |
| SCHEMBL4659414 | 0.82 | CTBP2 (0.54) | RAB9APOLBALDH1A1MAPK8 | |
| SCHEMBL27814786 | 0.81 | FFAR1 (0.49) | RAB9ASRCPOLBVNN1MAPK1 | |
| SCHEMBL11178482 | 0.81 | SRC (0.55) | RAB9ASRCPOLBVNN1CNR2 | |
| SCHEMBL4582402 | 0.81 | CES1 (0.52) | RAB9AALDH1A1 | |
| SCHEMBL4659471 | 0.80 | MEN1 (0.58) | RAB9APOLBALDH1A1SIGMAR1MAPK8 | |
| SCHEMBL7965958 | 0.80 | RAB9A (0.51) | RAB9APOLBVNN1TP53ALDH1A1 | |
| SCHEMBL3109722 | 0.80 | SRC (0.61) | RAB9ASRCPOLBTP53ALDH1A1 | |
| SCHEMBL29699631 | 0.80 | SRC (0.61) | RAB9ASRCPOLBTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004166-A2 | INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT AND PREVENTION OF DISEASES | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007120528-A2 | INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT AND PREVENTION OF DISEASES | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2007-10-25 | — | — | WO | disclosed |