Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29244022 | 0.79 | DGAT1 (0.48) | DGAT1ELANE | |
| SCHEMBL808799 | 0.74 | DGAT1 (0.74) | DGAT1ELANE | |
| SCHEMBL23091415 | 0.72 | DGAT1 (0.70) | DGAT1ELANE | |
| Ammonia Solution, Strong SCHEMBL7639328 | 0.72 | DGAT1 (0.70) | DGAT1ELANE | |
| Iodide SCHEMBL10533676 | 0.72 | DGAT1 (0.70) | DGAT1ELANE | |
| SCHEMBL10773556 | 0.71 | DGAT1 (0.45) | DGAT1ELANE | |
| SCHEMBL13910253 | 0.69 | MEN1 (0.32) | — | |
| SCHEMBL5859056 | 0.69 | DGAT1 (0.59) | DGAT1ELANE | |
| SCHEMBL18827813 | 0.69 | DGAT1 (0.52) | DGAT1ELANE | |
| SCHEMBL1010735 | 0.67 | DGAT1 (0.56) | DGAT1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101466725-B | Amino derivatives of androstanes and androstenes as medicaments for cardiovascular disorders | SIGMA TAU IND FARMACEUTI | 2014-06-25 | — | — | CN | disclosed |
| US-8609644-B2 | Amino derivatives of androstanes and androstenes as medicaments for cardiovascular disorders | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2013-12-17 | — | — | US | disclosed |
| EP-2004668-B1 | AMINO DERIVATIVES OF ANDROSTANES AND ANDROSTENES AS MEDICAMENTS FOR CARDIOVASCULAR DISORDERS | SIGMA TAU IND FARMACEUTI (IT) | 2013-03-13 | — | — | EP | disclosed |
| US-20110053902-A1 | AMINO DERIVATIVES OF ANDROSTANES AND ANDROSTENES AS MEDICAMENTS FOR CARDIOVASCULAR DISORDERS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2011-03-03 | — | — | US | disclosed |
| CN-101466725-A | Amino derivatives of androstanes and androstenes as medicaments for cardiovascular disorders | SIGMA TAU IND FARMACEUTI (IT) | 2009-06-24 | — | — | CN | disclosed |
| EP-2004668-A2 | AMINO DERIVATIVES OF ANDROSTANES AND ANDROSTENES AS MEDICAMENTS FOR CARDIOVASCULAR DISORDERS | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. (IT) | 2008-12-24 | — | — | EP | disclosed |
| WO-2007118832-A2 | AMINO DERIVATIVES OF ANDROSTANES AND ANDROSTENES AS MEDICAMENTS FOR CARDIOVASCULAR DISORDERS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053902-A1 | AMINO DERIVATIVES OF ANDROSTANES AND ANDROSTENES AS MEDICAMENTS FOR CARDIOVASCULAR DISORDERS | PKD1, ATP1A2, ATP1A1 | DGAT1 2538/4885ELANE 1962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.