Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 3/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661305 | 0.82 | PYCR1 (0.42) | NPC1ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL4661399 | 0.82 | PYCR1 (0.42) | NPC1ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL4661365 | 0.79 | ACACB (0.43) | MMP2MMP13 | |
| SCHEMBL4662731 | 0.76 | PTPN1 (0.34) | MMP2MMP9MMP8MMP13CYP11B1 | |
| SCHEMBL4662702 | 0.76 | JAK2 (0.42) | AOC3RAB9A | |
| SCHEMBL4661242 | 0.73 | POLB (0.45) | LMNASMN1; SMN2KDM4E | |
| SCHEMBL4661323 | 0.73 | ALDH1A1 (0.41) | MMP2MMP9MMP8MMP13ALDH1A1 | |
| SCHEMBL4661500 | 0.73 | ALDH1A1 (0.41) | MMP2MMP9MMP8MMP13ALDH1A1 | |
| SCHEMBL4664189 | 0.72 | TYMS (0.46) | MMP2MMP9MMP8MMP13ALDH1A1 | |
| SCHEMBL4346767 | 0.72 | MEN1 (0.55) | AOC3RAB9AALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007707-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118041-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-10-18 | — | — | WO | disclosed |