Sugi Predict

Sugi Predict / Compounds / SCHEMBL46641

SCHEMBL46641

SCHEMBL46641

CSCC(NC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ PPARA Q07869 11/20 0.57
▸ PPARG P37231 10/20 0.57
▸ PPARD Q03181 2/20 0.54
▸ CTSS P25774 5/20 0.54
▸ CTSK P43235 5/20 0.54
▸ CYP1A2 P05177 1/20 0.52
▸ CYP2C9 P11712 1/20 0.52
▸ CYP2C19 P33261 1/20 0.52
▸ HTT P42858 1/20 0.52
▸ CTSL P07711 1/20 0.47
▸ CTSB P07858 1/20 0.47
▸ ACE P12821 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.45
▸ CA1 P00915 1/20 0.45
▸ CA2 P00918 1/20 0.45
▸ CA7 P43166 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1618767 1.00 PPARA (0.57) PPARAPPARGPPARDCTSSCTSK
SCHEMBL2313666 1.00 PPARA (0.57) PPARAPPARGPPARDCTSSCTSK
SCHEMBL13489723 0.89 PPARA (0.57) PPARAPPARGPPARDCTSSCTSK
SCHEMBL432222 0.89 PPARA (0.57) PPARAPPARGPPARDCTSSCTSK
SCHEMBL5351802 0.89 PPARA (0.57) PPARAPPARGPPARDCTSSCTSK
SCHEMBL23927278 0.89 PPARA (0.64) PPARAPPARGPPARDCTSSCTSK
SCHEMBL2541324 0.89 PPARA (0.57) PPARAPPARGPPARDCTSSCTSK
SCHEMBL316084 0.89 PPARA (0.57) PPARAPPARGPPARDCTSSCTSK
SCHEMBL9808989 0.89 PPARA (0.57) PPARAPPARGPPARDCTSSCTSK
SCHEMBL9808970 0.89 PPARA (0.57) PPARAPPARGPPARDCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116874803-A Antibacterial dendritic polyester polymer and preparation method and application thereof 清华大学深圳国际研究生院 2023-10-13 — — CN claimed
US-20250188040-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS VIVIDION THERAPEUTICS INC 2025-06-12 — — US disclosed
EP-4551555-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS Vividion Therapeutics, Inc. (US) 2025-05-14 — — EP disclosed
US-12187685-B2 Pharmaceutical compositions comprising WRN helicase inhibitors VIVIDION THERAPEUTICS, INC. 2025-01-07 — — US disclosed
US-12152048-B2 Nitroxoline prodrug and use thereof JIANGSU YAHONG MEDITECH CO., LTD. (CN) 2024-11-26 — — US disclosed
US-20240197666-A1 DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) K-GEN THERAPEUTICS, INC. (US) 2024-06-20 — — US disclosed
US-20240140915-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS VIVIDION THERAPEUTICS, INC. 2024-05-02 — — US disclosed
US-20240067612-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS VIVIDION THERAPEUTICS, INC. 2024-02-29 — — US disclosed
EP-4313095-A1 DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) K-Gen Therapeutics, Inc. (US) 2024-02-07 — — EP disclosed
WO-2024010782-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS VIVIDION THERAPEUTICS, INC. (US) 2024-01-11 — — WO disclosed
EP-0891329-A1 PEPTIDYL COMPOUNDS HAVING MMP AND TNF INHIBITORY ACTIVITY Darwin Discovery Limited (GB) 1999-01-20 — — EP disclosed
EP-0574135-B1 Process for producing peptide derivatives and salts thereof JAPAN ENERGY CORP (JP) 1998-11-18 — — EP disclosed
WO-1997037974-A1 PEPTIDYL COMPOUNDS HAVING MMP AND TNF INHIBITORY ACTIVITY DARWIN DISCOVERY LIMITED (GB) 1997-10-16 — — WO disclosed
US-5644028-A Process for producing peptide derivatives and salts therefor JAPAN ENERGY CORPORATION (JP) 1997-07-01 — — US disclosed
US-5442044-A Hypotensive agents PFIZER INC. (US) 1995-08-15 — — US disclosed
EP-0661292-A1 Orally active renin inhibitors PFIZER INC. (US) 1995-07-05 — — EP disclosed
EP-0574135-A1 Process for producing peptide derivatives and salts thereof JAPAN ENERGY CORPORATION (JP) 1993-12-15 — — EP disclosed
US-5227398-A BENZODIOXOLE DERIVATIVES AND HEPATOPATHY IMPROVERS COMPRISING THE SAME TSUMURA & CO. (JP) 1993-07-13 — — US disclosed
EP-0488144-A1 Benzodioxole derivatives and hepatopathy improvers comprising the same TSUMURA & CO. (JP) 1992-06-03 — — EP disclosed
EP-0438233-A2 Orally active renin inhibitors PFIZER INC. (US) 1991-07-24 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12152048-B2 Nitroxoline prodrug and use thereof NOS1, NOS2, NNT PPARA 2229/4885PPARG 2354/4885PPARD 1981/4885
US-20240067612-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS RECQL, BLM, WRN PPARA 3369/4885PPARG 3244/4885PPARD 3372/4885
US-20240140915-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS RECQL, BLM, WRN PPARA 3369/4885PPARG 3244/4885PPARD 3372/4885
US-12187685-B2 Pharmaceutical compositions comprising WRN helicase inhibitors RECQL, BLM, WRN PPARA 3369/4885PPARG 3244/4885PPARD 3372/4885
US-20250188040-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS RECQL, BLM, WRN PPARA 3369/4885PPARG 3244/4885PPARD 3372/4885
US-20240197666-A1 DITERPENOID COMPOUNDS THAT ACT ON PROTEIN KINASE C (PKC) PRKCA, PRKCB, PRKCI PPARA 947/4885PPARG 620/4885PPARD 1268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.