Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665755 | 0.86 | OPRM1 (0.45) | OPRM1OPRL1DPP4HDAC4SIGMAR1 | |
| SCHEMBL4665563 | 0.81 | OPRM1 (0.46) | OPRM1OPRL1DPP4SIGMAR1TMEM97 | |
| SCHEMBL4663430 | 0.77 | OPRM1 (0.43) | OPRM1OPRL1OPRD1OPRK1 | |
| SCHEMBL29025309 | 0.76 | MAOB (0.42) | OPRM1OPRL1HDAC4OPRD1OPRK1 | |
| SCHEMBL156982 | 0.76 | MAOB (0.42) | OPRM1OPRL1HDAC4OPRD1OPRK1 | |
| SCHEMBL4667288 | 0.74 | OPRM1 (0.42) | OPRM1OPRL1DPP4 | |
| SCHEMBL4665572 | 0.74 | OPRL1 (0.47) | OPRM1OPRL1HDAC4OPRD1OPRK1 | |
| SCHEMBL11945826 | 0.69 | OPRM1 (0.55) | OPRM1OPRL1DPP4HDAC4SIGMAR1 | |
| SCHEMBL4663490 | 0.67 | OPRM1 (0.46) | OPRM1OPRL1DPP4OPRD1OPRK1 | |
| SCHEMBL22488577 | 0.67 | OPRM1 (0.61) | OPRM1OPRL1DPP4HDAC4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1571140-B1 | C-substituted cyclohexylmethylamine derivatives | GRUENENTHAL GMBH (DE) | 2008-11-12 | — | — | EP | claimed |