Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665563 | 0.87 | OPRM1 (0.46) | OPRM1OPRL1DPP4SLC6A4SLC6A3 | |
| SCHEMBL4664216 | 0.86 | OPRM1 (0.45) | OPRM1OPRL1DPP4HDAC4TMEM97 | |
| SCHEMBL4667288 | 0.80 | OPRM1 (0.42) | OPRM1OPRL1DPP4SLC6A4 | |
| SCHEMBL4665572 | 0.79 | OPRL1 (0.47) | OPRM1OPRL1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL4663777 | 0.77 | OPRK1 (0.45) | OPRM1OPRL1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL29025309 | 0.76 | MAOB (0.42) | OPRM1OPRL1SLC6A4SLC6A2HDAC4 | |
| SCHEMBL156982 | 0.76 | MAOB (0.42) | OPRM1OPRL1SLC6A4SLC6A2HDAC4 | |
| SCHEMBL11945826 | 0.69 | OPRM1 (0.55) | OPRM1OPRL1DPP4HDAC4TMEM97 | |
| SCHEMBL18622454 | 0.68 | OPRM1 (0.60) | OPRM1OPRL1DPP4DRD4DRD3 | |
| SCHEMBL4663490 | 0.67 | OPRM1 (0.46) | OPRM1OPRL1DPP4SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1571140-B1 | C-substituted cyclohexylmethylamine derivatives | GRUENENTHAL GMBH (DE) | 2008-11-12 | — | — | EP | claimed |