Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665755 | 0.80 | OPRM1 (0.45) | OPRM1OPRL1SLC6A4DPP4 | |
| SCHEMBL4663961 | 0.77 | OPRK1 (0.43) | OPRM1OPRL1HTR2CHTR2BSLC6A4 | |
| SCHEMBL4665563 | 0.77 | OPRM1 (0.46) | OPRM1OPRL1SLC6A4NPC1RAB9A | |
| SCHEMBL4664216 | 0.74 | OPRM1 (0.45) | OPRM1OPRL1DPP4 | |
| SCHEMBL156982 | 0.69 | MAOB (0.42) | OPRM1OPRL1SLC6A4SMN1; SMN2 | |
| SCHEMBL29025309 | 0.69 | MAOB (0.42) | OPRM1OPRL1SLC6A4SMN1; SMN2 | |
| SCHEMBL11945826 | 0.69 | OPRM1 (0.55) | OPRM1OPRL1DPP4 | |
| SCHEMBL4664102 | 0.66 | OPRM1 (0.45) | OPRM1OPRL1SLC6A4SMN1; SMN2DPP4 | |
| SCHEMBL22488577 | 0.66 | OPRM1 (0.61) | OPRM1OPRL1DPP4 | |
| SCHEMBL4665572 | 0.65 | OPRL1 (0.47) | OPRM1OPRL1HTR2CHTR2BSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1571140-B1 | C-substituted cyclohexylmethylamine derivatives | GRUENENTHAL GMBH (DE) | 2008-11-12 | — | — | EP | claimed |