Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665755 | 0.87 | OPRM1 (0.45) | OPRM1OPRL1DPP4SLC6A4SLC6A3 | |
| SCHEMBL4664216 | 0.81 | OPRM1 (0.45) | OPRM1OPRL1DPP4SIGMAR1TMEM97 | |
| SCHEMBL4665572 | 0.78 | OPRL1 (0.47) | OPRM1OPRL1SLC6A4SLC6A3CCR2 | |
| SCHEMBL4667288 | 0.77 | OPRM1 (0.42) | OPRM1OPRL1DPP4SLC6A4NPC1 | |
| SCHEMBL4665560 | 0.77 | OPRM1 (0.44) | OPRM1OPRL1DPP4SLC6A4SLC6A3 | |
| SCHEMBL29025309 | 0.73 | MAOB (0.42) | OPRM1OPRL1SLC6A4 | |
| SCHEMBL156982 | 0.73 | MAOB (0.42) | OPRM1OPRL1SLC6A4 | |
| SCHEMBL11945826 | 0.70 | OPRM1 (0.55) | OPRM1OPRL1DPP4SIGMAR1TMEM97 | |
| SCHEMBL4665358 | 0.68 | SLC6A4 (0.46) | OPRM1OPRL1SLC6A4SLC6A3 | |
| SCHEMBL22488577 | 0.67 | OPRM1 (0.61) | OPRM1OPRL1DPP4SIGMAR1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1571140-B1 | C-substituted cyclohexylmethylamine derivatives | GRUENENTHAL GMBH (DE) | 2008-11-12 | — | — | EP | claimed |