SCHEMBL466426

SCHEMBL466426

Oc1ccc(-c2nccs2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.63
LOXL2 Q9Y4K0 1/20 0.60
ADRB2 P07550 2/20 0.55
ESR1 P03372 2/20 0.50
ESR2 Q92731 1/20 0.50
SYK P43405 1/20 0.50
CYP2A6 P11509 1/20 0.50
SMPD3 Q9NY59 1/20 0.49
FBP1 P09467 1/20 0.47
ABL1 P00519 1/20 0.46
BCR P11274 1/20 0.46
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC10 Q969S8 1/20 0.44
HDAC11 Q96DB2 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL29239355 0.98 PDPK1 (0.61) PDPK1LOXL2ADRB2ESR1ESR2
SCHEMBL2295510 0.89 PDPK1 (0.52) PDPK1LOXL2ADRB2ESR1ESR2
SCHEMBL722198 0.89 PDPK1 (0.77) PDPK1LOXL2ADRB2CYP2A6SMPD3
SCHEMBL23328027 0.81 ESR1 (0.50) PDPK1LOXL2ADRB2ESR1ESR2
Ethoxycarbonyl Group SCHEMBL29291640 0.81 ADRB2 (0.47) PDPK1LOXL2ADRB2ESR1ESR2
SCHEMBL17704291 0.80 PDPK1 (0.65) PDPK1LOXL2ADRB2CYP2A6SMPD3
SCHEMBL533419 0.79 LOXL2 (0.67) PDPK1LOXL2ADRB2CYP2A6SMPD3
SCHEMBL10576999 0.78 PDPK1 (0.63) PDPK1LOXL2ADRB2CYP2A6SMPD3
SCHEMBL16119908 0.78 PDPK1 (0.63) PDPK1LOXL2ADRB2CYP2A6SMPD3
SCHEMBL21791658 0.78 LOXL2 (0.71) PDPK1LOXL2ADRB2CYP2A6SMPD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250270199-A1 THIAZOLE DERIVATIVES AND METHODS OF USING THE SAME ARKANSAS STATE UNIV JONESBORO (US) 2025-08-28 US claimed
EP-3494396-B1 CHEMILUMINESCENT AND FLUORESCENT SUBSTRATE PADS AND USES THEREOF PIERCE BIOTECHNOLOGY INC (US) 2025-06-11 EP claimed
CN-115724641-B Mildew-proof antibacterial autoclaved aerated block and preparation method thereof 广州市贤达建材有限公司 2024-02-23 CN claimed
WO-2023192595-A1 THIAZOLE DERIVATIVES AND METHODS OF USING THE SAME Arkansas State University - Jonesboro (US) 2023-10-05 WO claimed
CN-116836127-A Hybrid bismuth-chloride material and reversible photochromic application 济南大学 2023-10-03 CN claimed
CN-115724641-A Mildew-proof antibacterial autoclaved aerated building block and preparation method thereof 广州市贤达建材有限公司 2023-03-03 CN claimed
EP-0938677-A4 CHEMILUMINESCENT DETECTION METHODS USING DUAL ENZYME-LABELED BINDING PARTNERS LUMIGEN INC (US) 2000-09-27 EP claimed
EP-0938677-A1 CHEMILUMINESCENT DETECTION METHODS USING DUAL ENZYME-LABELED BINDING PARTNERS LUMIGEN, INC. (US) 1999-09-01 EP claimed
US-5843666-A Chemiluminescent detection methods using dual enzyer-labeled binding partners LUMIGEN, INC. (US) 1998-12-01 US claimed
WO-1998021586-A1 CHEMILUMINESCENT DETECTION METHODS USING DUAL ENZYME-LABELED BINDING PARTNERS LUMIGEN, INC. (US) 1998-05-22 WO claimed
JP-6329647-A None JP disclosed
CN-116836127-B Hybrid bismuth-chloride material and reversible photochromic application 济南大学 2025-09-26 CN disclosed
US-20250270199-A1 THIAZOLE DERIVATIVES AND METHODS OF USING THE SAME ARKANSAS STATE UNIV JONESBORO (US) 2025-08-28 US disclosed
US-20250270199-A1 THIAZOLE DERIVATIVES AND METHODS OF USING THE SAME ARKANSAS STATE UNIV JONESBORO (US) 2025-08-28 US disclosed
US-20250216782-A1 MASKING PROCESS USING SWITCHABLE POLYMER TOKYO ELECTRON LTD (JP) 2025-07-03 US disclosed
EP-0556123-A1 Pyrethrinoid esters of thiazolylalcohols, process for their preparation and their use as pesticides ROUSSEL UCLAF (FR) 1993-08-18 EP disclosed
EP-0343307-A1 4-Piperidinealkanamine derivatives FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. (ES) 1989-11-29 EP disclosed
EP-0039892-B1 SUBSTITUTED PHENYL ETHERS CIBA-GEIGY AG (CH) 1986-12-30 EP disclosed
US-4559354-A ADRENERGIC BLOCKING AGENTS AND STIMULANTS; CARDIOTONIC, ANTIARRHYTHMIA AND INOTROPIC AGENTS CIBA-GEIGY CORPORATION (US) 1985-12-17 US disclosed
EP-0039892-A1 Substituted phenyl ethers CIBA-GEIGY AG (CH) 1981-11-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250270199-A1 THIAZOLE DERIVATIVES AND METHODS OF USING THE SAME TST, GOT2, TPMT PDPK1 3270/4885LOXL2 722/4885ADRB2 2372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.