Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 1/20 | 0.36 |
| ▸ | ATP4B | P51164 | 1/20 | 0.36 |
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
| ▸ | SLC8A1 | P32418 | 6/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL5656929 | 0.95 | RAB9A (0.35) | ATP4AATP4BSLC8A1RAB9AF2 | |
| SCHEMBL5661208 | 0.92 | ATP4A (0.34) | ATP4AATP4BPTAFRSLC8A1 | |
| SCHEMBL4964853 | 0.88 | ADRA1A (0.31) | SLC8A1 | |
| SCHEMBL4662876 | 0.88 | ATP4A (0.37) | ATP4AATP4BSLC8A1RAB9ALMNA | |
| SCHEMBL4663178 | 0.80 | DHODH (0.36) | ATP4AATP4BSLC8A1RAB9ACYP19A1 | |
| SCHEMBL5506546 | 0.80 | ATP4A (0.35) | ATP4AATP4BRAB9ALMNA | |
| SCHEMBL6019450 | 0.80 | DHODH (0.36) | ATP4AATP4BSLC8A1RAB9ACYP19A1 | |
| SCHEMBL6020045 | 0.80 | DHODH (0.36) | ATP4AATP4BSLC8A1RAB9ACYP19A1 | |
| SCHEMBL4666543 | 0.78 | RAB9A (0.35) | ATP4AATP4BSLC8A1RAB9A | |
| SCHEMBL5506543 | 0.78 | RAB9A (0.35) | ATP4AATP4BSLC8A1RAB9ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113963-A1 | Cyclic benzimidazoles | ALTANA PHARMA AG (DE) | 2008-05-15 | — | — | US | disclosed |
| US-7307084-B2 | Cyclic benzimidazoles | ALTANA PHARMA AG (DE) | 2007-12-11 | — | — | US | disclosed |
| US-20060194968-A1 | Cyclic benizimidazoles | ALTANA PHARMA AG (DE) | 2006-08-31 | — | — | US | disclosed |
| EP-1613626-A1 | CYCLIC BENZIMIDAZOLES | ALTANA Pharma AG (DE) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004087701-A1 | CYCLIC BENZIMIDAZOLES | ALTANA PHARMA AG (DE) | 2004-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194968-A1 | Cyclic benizimidazoles | VIP, SI, GIPR | ATP4A 417/4885ATP4B 762/4885PTAFR 3915/4885 |
| US-20080113963-A1 | Cyclic benzimidazoles | VIP, GIPR, SI | ATP4A 120/4885ATP4B 129/4885PTAFR 4180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.