Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | PDE9A | O76083 | 2/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | ACLY | P53396 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3555267 | 0.80 | ALDH1A1 (0.34) | BRD4POLBALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL5901225 | 0.79 | CA12 (0.45) | BRD4PARP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4662894 | 0.76 | ACSS2 (0.34) | BRD4ALDH1A1 | |
| SCHEMBL4664646 | 0.76 | PDE9A (0.40) | BRD4ALDH1A1HSD17B10TLR7PDE9A | |
| SCHEMBL4663143 | 0.75 | HDAC4 (0.35) | ALDH1A1KEAP1NFE2L2 | |
| SCHEMBL5901229 | 0.72 | SLC9A3 (0.35) | PARP1ALDH1A1ALOX15HSD17B10HTR2B | |
| SCHEMBL8135378 | 0.72 | BRD4 (0.40) | BRD4PARP1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL4664629 | 0.70 | ALDH1A1 (0.41) | BRD4PARP1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL25647191 | 0.68 | L3MBTL1 (0.37) | ALDH1A1PIK3CDSMN1; SMN2KDM5AKDM2B | |
| SCHEMBL4664631 | 0.68 | PARP1 (0.36) | BRD4PARP1ALDH1A1ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113963-A1 | Cyclic benzimidazoles | ALTANA PHARMA AG (DE) | 2008-05-15 | — | — | US | disclosed |
| US-7307084-B2 | Cyclic benzimidazoles | ALTANA PHARMA AG (DE) | 2007-12-11 | — | — | US | disclosed |
| US-20060194968-A1 | Cyclic benizimidazoles | ALTANA PHARMA AG (DE) | 2006-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194968-A1 | Cyclic benizimidazoles | VIP, SI, GIPR | BRD4 85/4885POLB 3725/4885PARP1 3691/4885 |
| US-20080113963-A1 | Cyclic benzimidazoles | VIP, GIPR, SI | BRD4 1068/4885POLB 2837/4885PARP1 3997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.