Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1527710 | 0.97 | CA2 (0.42) | CA2RECQLALDH1A1TSHRCYP3A4 | |
| Potassium Ion SCHEMBL817854 | 0.90 | CA2 (0.40) | CA2RECQLALDH1A1TSHRCYP3A4 | |
| SCHEMBL2425804 | 0.87 | CA2 (0.40) | CA2RECQLALDH1A1TSHRCYP3A4 | |
| SCHEMBL9949603 | 0.87 | CA2 (0.40) | CA2RECQLALDH1A1TSHRCYP3A4 | |
| SCHEMBL11119598 | 0.87 | CA2 (0.40) | CA2RECQLALDH1A1TSHRCYP3A4 | |
| SCHEMBL51225 | 0.87 | CA2 (0.42) | CA2RECQLALDH1A1TSHRCYP3A4 | |
| Silver SCHEMBL2027796 | 0.87 | CA2 (0.40) | CA2RECQLALDH1A1TSHRCYP3A4 | |
| SCHEMBL2027800 | 0.87 | CA2 (0.40) | CA2RECQLALDH1A1TSHRCYP3A4 | |
| Tetramethylammonium Ion SCHEMBL5525956 | 0.85 | CA2 (0.38) | CA2RECQLALDH1A1TSHRCYP3A4 | |
| SCHEMBL5485773 | 0.80 | CA2 (0.39) | CA2RECQLALDH1A1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9464218-B2 | (Meth)acrylate polymer, a resin composition and a shaped article | MITSUBISHI RAYON CO., LTD. (JP) | 2016-10-11 | — | — | US | disclosed |
| US-20160024355-A1 | (METH)ACRYLATE POLYMER, A RESIN COMPOSITION AND A SHAPED ARTICLE | MITSUBISHI RAYON CO., LTD. (JP) | 2016-01-28 | — | — | US | disclosed |
| EP-2407497-B1 | (METH)ACRYLATE POLYMER, RESIN COMPOSITION, AND MOLDED ARTICLE | MITSUBISHI RAYON CO (JP) | 2014-10-15 | — | — | EP | disclosed |
| US-20120123023-A1 | (METH)ACRYLATE POLYMER, A RESIN COMPOSITION AND A SHAPED ARTICLE | MITSUBISHI RAYON CO., LTD. (JP) | 2012-05-17 | — | — | US | disclosed |
| EP-2407497-A1 | (METH)ACRYLATE POLYMER, RESIN COMPOSITION, AND MOLDED ARTICLE | Mitsubishi Rayon Co., Ltd. (JP) | 2012-01-18 | — | — | EP | disclosed |