SCHEMBL4665371

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4665379	0.95	OPRK1 (0.42)	OPRK1OPRD1OPRM1SLC6A4SLC6A2
	SCHEMBL4665354	0.90	DRD2 (0.41)	OPRK1OPRD1OPRM1SLC6A4SLC6A2
	SCHEMBL4663483	0.90	DRD2 (0.41)	OPRK1OPRD1OPRM1SLC6A4SLC6A2
	SCHEMBL4664046	0.90	SMN1; SMN2 (0.48)	OPRK1OPRD1OPRM1SLC6A4SLC6A2
	Hydrochloric Acid SCHEMBL8609536	0.89	OPRK1 (0.42)	OPRK1OPRD1OPRM1SLC6A4SLC6A2
	SCHEMBL4663393	0.89	OPRM1 (0.39)	OPRK1OPRD1OPRM1SLC6A4SLC6A2
	SCHEMBL4665499	0.89	ALDH1A1 (0.46)	OPRK1OPRD1OPRM1SLC6A4SLC6A2
	SCHEMBL4665474	0.88	OPRK1 (0.43)	OPRK1OPRD1OPRM1SLC6A4SLC6A2
	SCHEMBL4663567	0.88	SMN1; SMN2 (0.43)	OPRK1OPRD1OPRM1SLC6A4SLC6A2
	SCHEMBL4663555	0.87	OPRK1 (0.47)	OPRK1OPRD1OPRM1SLC6A4SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.