Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 10/20 | 0.55 |
| ▸ | CA9 | Q16790 | 10/20 | 0.55 |
| ▸ | CA1 | P00915 | 9/20 | 0.55 |
| ▸ | CA12 | O43570 | 4/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 2/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.45 |
| ▸ | FEN1 | P39748 | 2/20 | 0.45 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4667170 | 0.88 | CA2 (0.58) | CA2CA9CA1CA12STAT3 | |
| SCHEMBL4667208 | 0.83 | STAT3 (0.64) | KDM1AMCL1STAT3CDK1CDK2 | |
| SCHEMBL31645593 | 0.79 | KDM1A (0.60) | KDM1ACA2CA9CA12MCL1 | |
| SCHEMBL4533547 | 0.79 | KDM1A (0.60) | KDM1ACA2CA9CA12MCL1 | |
| SCHEMBL7183442 | 0.78 | LMNA (0.64) | KDM1ACA2CA9CA12MCL1 | |
| SCHEMBL4667179 | 0.76 | MCL1 (0.61) | KDM1ACA2CA9CA12MCL1 | |
| SCHEMBL7183438 | 0.76 | KDM1A (0.58) | KDM1ACA2CA9CA12MCL1 | |
| SCHEMBL4668685 | 0.76 | CA2 (0.62) | CA2CA9CA1CA12STS | |
| SCHEMBL4667780 | 0.76 | KIF11 (0.59) | CA2CA9CA1CA12STS | |
| SCHEMBL4665426 | 0.73 | CA2 (0.62) | CA2CA9CA1CA12STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193250-B1 | PHENYL SULFAMATE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |