SCHEMBL466646

SCHEMBL466646

CCCCCCCC/C=C/CCCCCCCC(=O)C(O)C(N)(C(=O)CCCCCCC/C=C/CCCCCCCC)P(=O)(O)O

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ FAAH O00519 6/20 0.51
▸ SOAT1 P35610 2/20 0.51
▸ MEN1 O00255 1/20 0.51
▸ TP53 P04637 1/20 0.51
▸ CYP1A2 P05177 1/20 0.51
▸ CYP3A4 P08684 1/20 0.51
▸ CYP2C19 P33261 1/20 0.51
▸ KMT2A Q03164 1/20 0.51
▸ CES1 P23141 2/20 0.50
▸ KDM4E B2RXH2 2/20 0.48
▸ FABP3 P05413 5/20 0.47
▸ LPAR1 Q92633 4/20 0.44
▸ CES2 O00748 1/20 0.44
▸ ENPP2 Q13822 1/20 0.44
▸ LPAR4 Q99677 1/20 0.44
▸ LPAR5 Q9H1C0 1/20 0.44
▸ LPAR2 Q9HBW0 1/20 0.44
▸ LPAR3 Q9UBY5 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL466712 1.00 FAAH (0.51) FAAHSOAT1MEN1TP53CYP1A2
SCHEMBL466851 1.00 FAAH (0.51) FAAHSOAT1MEN1TP53CYP1A2
SCHEMBL466745 0.96 KDM4E (0.55) FAAHSOAT1MEN1TP53CYP1A2
SCHEMBL466582 0.92 SMPD1 (0.44) FAAHMEN1CYP1A2KMT2ACES1
SCHEMBL466941 0.92 SMPD1 (0.44) FAAHMEN1CYP1A2KMT2ACES1
SCHEMBL466673 0.92 SMPD1 (0.44) FAAHMEN1CYP1A2KMT2ACES1
SCHEMBL466752 0.92 SMPD1 (0.44) FAAHMEN1CYP1A2KMT2ACES1
SCHEMBL466809 0.91 FDPS (0.42) FAAHMEN1CYP1A2KMT2ACES1
SCHEMBL1394914 0.78 FAAH (0.58) FAAHSOAT1MEN1TP53CYP1A2
SCHEMBL637887 0.78 FAAH (0.58) FAAHSOAT1MEN1TP53CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9315828-B2 Prompt nucleic acid delivery carrier composition Takeuchi, Hirofumi (JP) 2016-04-19 — — US disclosed
US-9090912-B1 Nucleic acid complex and nucleic acid-delivering composition Takeuchi, Hirofumi (JP) 2015-07-28 — — US disclosed
EP-2405001-B1 NUCLEIC ACID COMPLEX AND NUCLEIC ACID-DELIVERING COMPOSITION TAKEUCHI HIROFUMI (JP) 2015-07-08 — — EP disclosed
EP-2140870-B1 PROMPT NUCLEIC ACID DELIVERY CARRIER COMPOSITION OTSUKA PHARMA CO LTD (JP) 2015-06-24 — — EP disclosed
EP-1946761-B1 CARRIER COMPOSITION FOR NUCLEIC ACID TRANSPORT OTSUKA PHARMA CO LTD (JP) 2013-04-03 — — EP disclosed
US-8338584-B2 Nucleic acid complex and nucleic acid delivery composition OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2012-12-25 — — US disclosed
EP-2405001-A1 NUCLEIC ACID COMPLEX AND NUCLEIC ACID-DELIVERING COMPOSITION Takeuchi, Hirofumi (JP) 2012-01-11 — — EP disclosed
US-8030075-B2 Carrier composition for nucleic acid transport OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2011-10-04 — — US disclosed
EP-2217208-B1 NUCLEIC ACID COMPLEX AND NUCLEIC ACID DELIVERY COMPOSITION OTSUKA PHARMA CO LTD (JP) 2011-08-31 — — EP disclosed
US-20100305190-A1 NUCLEIC ACID COMPLEX AND NUCLEIC ACID DELIVERY COMPOSITION Takeuchi, Hirofumi (JP) 2010-12-02 — — US disclosed
US-20100063131-A1 PROMPT NUCLEIC ACID DELIVERY CARRIER COMPOSITION Takeuchi, Hirofumi (JP) 2010-03-11 — — US disclosed
EP-2140870-A1 PROMPT NUCLEIC ACID DELIVERY CARRIER COMPOSITION Otsuka Pharmaceutical Co., Ltd. (JP) 2010-01-06 — — EP disclosed
US-20090258923-A1 Carrier Composition for Nucleic Acid Transport OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2009-10-15 — — US disclosed
EP-1946761-A1 CARRIER COMPOSITION FOR NUCLEIC ACID TRANSPORT Otsuka Pharmaceutical Co., Ltd. (JP) 2008-07-23 — — EP disclosed
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