SCHEMBL466745

SCHEMBL466745

CCCCC/C=C\C/C=C\CCCCCCCC(=O)C(O)C(N)(C(=O)CCCCCCC/C=C\C/C=C\CCCCC)P(=O)(O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.55
▸ SOAT1 P35610 2/20 0.55
▸ FABP3 P05413 3/20 0.50
▸ CNR1 P21554 1/20 0.49
▸ ALDH1A1 P00352 5/20 0.48
▸ FAAH O00519 5/20 0.48
▸ PLA2G4B P0C869 1/20 0.48
▸ MAPT P10636 1/20 0.48
▸ PLA2G4A P47712 1/20 0.48
▸ BLM P54132 1/20 0.48
▸ MGLL Q99685 1/20 0.48
▸ PLA2G4C Q9UP65 1/20 0.48
▸ F7 P08709 3/20 0.48
▸ F3 P13726 3/20 0.48
▸ PPARG P37231 2/20 0.48
▸ PPARD Q03181 2/20 0.48
▸ PPARA Q07869 2/20 0.48
▸ CYP3A4 P08684 2/20 0.48
▸ FFAR1 O14842 2/20 0.48
▸ DUSP3 P51452 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL466712 0.96 FAAH (0.51) KDM4ESOAT1FABP3FAAHCYP3A4
SCHEMBL466646 0.96 FAAH (0.51) KDM4ESOAT1FABP3FAAHCYP3A4
SCHEMBL466851 0.96 FAAH (0.51) KDM4ESOAT1FABP3FAAHCYP3A4
SCHEMBL466941 0.89 SMPD1 (0.44) FAAHHSD17B10MEN1CYP1A2KMT2A
SCHEMBL466582 0.89 SMPD1 (0.44) FAAHHSD17B10MEN1CYP1A2KMT2A
SCHEMBL466673 0.89 SMPD1 (0.44) FAAHHSD17B10MEN1CYP1A2KMT2A
SCHEMBL466752 0.89 SMPD1 (0.44) FAAHHSD17B10MEN1CYP1A2KMT2A
SCHEMBL466809 0.87 FDPS (0.42) FAAHHSD17B10MEN1CYP1A2KMT2A
SCHEMBL5705311 0.80 ALDH1A1 (0.55) KDM4ESOAT1FABP3ALDH1A1FAAH
SCHEMBL3051999 0.77 ALDH1A1 (0.51) KDM4ESOAT1FABP3ALDH1A1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9315828-B2 Prompt nucleic acid delivery carrier composition Takeuchi, Hirofumi (JP) 2016-04-19 — — US disclosed
US-9090912-B1 Nucleic acid complex and nucleic acid-delivering composition Takeuchi, Hirofumi (JP) 2015-07-28 — — US disclosed
EP-2405001-B1 NUCLEIC ACID COMPLEX AND NUCLEIC ACID-DELIVERING COMPOSITION TAKEUCHI HIROFUMI (JP) 2015-07-08 — — EP disclosed
EP-2140870-B1 PROMPT NUCLEIC ACID DELIVERY CARRIER COMPOSITION OTSUKA PHARMA CO LTD (JP) 2015-06-24 — — EP disclosed
WO-2015055630-A1 COMPOSITIONS FOR TRANSFECTING NUCLEIC ACID MOLECULES INTO EUKARYOTIC CELLS TECHNISCHE UNIVERSITÄT GRAZ (AT) 2015-04-23 — — WO disclosed
EP-2860255-A1 Compositions comprising cationic and neutral lipids for transfecting nucleic acid molecules into eukaryotic cells Technische Universität Graz (AT) 2015-04-15 — — EP disclosed
EP-1946761-B1 CARRIER COMPOSITION FOR NUCLEIC ACID TRANSPORT OTSUKA PHARMA CO LTD (JP) 2013-04-03 — — EP disclosed
US-8338584-B2 Nucleic acid complex and nucleic acid delivery composition OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2012-12-25 — — US disclosed
EP-2405001-A1 NUCLEIC ACID COMPLEX AND NUCLEIC ACID-DELIVERING COMPOSITION Takeuchi, Hirofumi (JP) 2012-01-11 — — EP disclosed
US-8030075-B2 Carrier composition for nucleic acid transport OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2011-10-04 — — US disclosed
EP-2217208-B1 NUCLEIC ACID COMPLEX AND NUCLEIC ACID DELIVERY COMPOSITION OTSUKA PHARMA CO LTD (JP) 2011-08-31 — — EP disclosed
US-20100305190-A1 NUCLEIC ACID COMPLEX AND NUCLEIC ACID DELIVERY COMPOSITION Takeuchi, Hirofumi (JP) 2010-12-02 — — US disclosed
EP-2217208-A2 NUCLEIC ACID COMPLEX AND NUCLEIC ACID DELIVERY COMPOSITION Otsuka Pharmaceutical Co., Ltd. (JP) 2010-08-18 — — EP disclosed
US-20100063131-A1 PROMPT NUCLEIC ACID DELIVERY CARRIER COMPOSITION Takeuchi, Hirofumi (JP) 2010-03-11 — — US disclosed
EP-2140870-A1 PROMPT NUCLEIC ACID DELIVERY CARRIER COMPOSITION Otsuka Pharmaceutical Co., Ltd. (JP) 2010-01-06 — — EP disclosed
US-20090258923-A1 Carrier Composition for Nucleic Acid Transport OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2009-10-15 — — US disclosed
WO-2009061003-A2 NUCLEIC ACID COMPLEX AND NUCLEIC ACID DELIVERY COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2009-05-14 — — WO disclosed
EP-1946761-A1 CARRIER COMPOSITION FOR NUCLEIC ACID TRANSPORT Otsuka Pharmaceutical Co., Ltd. (JP) 2008-07-23 — — EP disclosed
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