Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 5/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL466582 | 0.98 | SMPD1 (0.44) | FDPSSMPD1FAAHCES1CES2 | |
| SCHEMBL466673 | 0.98 | SMPD1 (0.44) | FDPSSMPD1FAAHCES1CES2 | |
| SCHEMBL466752 | 0.98 | SMPD1 (0.44) | FDPSSMPD1FAAHCES1CES2 | |
| SCHEMBL466941 | 0.98 | SMPD1 (0.44) | FDPSSMPD1FAAHCES1CES2 | |
| SCHEMBL466712 | 0.91 | FAAH (0.51) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL466646 | 0.91 | FAAH (0.51) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL466851 | 0.91 | FAAH (0.51) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL466745 | 0.87 | KDM4E (0.55) | FAAHCES1MEN1CYP1A2KMT2A | |
| SCHEMBL9754746 | 0.73 | FAAH (0.48) | FAAHCES1CES2MEN1CYP1A2 | |
| SCHEMBL18092236 | 0.73 | CES2 (0.52) | FAAHCES1CES2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315828-B2 | Prompt nucleic acid delivery carrier composition | Takeuchi, Hirofumi (JP) | 2016-04-19 | — | — | US | disclosed |
| US-9090912-B1 | Nucleic acid complex and nucleic acid-delivering composition | Takeuchi, Hirofumi (JP) | 2015-07-28 | — | — | US | disclosed |
| EP-2405001-B1 | NUCLEIC ACID COMPLEX AND NUCLEIC ACID-DELIVERING COMPOSITION | TAKEUCHI HIROFUMI (JP) | 2015-07-08 | — | — | EP | disclosed |
| EP-2140870-B1 | PROMPT NUCLEIC ACID DELIVERY CARRIER COMPOSITION | OTSUKA PHARMA CO LTD (JP) | 2015-06-24 | — | — | EP | disclosed |
| EP-1946761-B1 | CARRIER COMPOSITION FOR NUCLEIC ACID TRANSPORT | OTSUKA PHARMA CO LTD (JP) | 2013-04-03 | — | — | EP | disclosed |
| US-8338584-B2 | Nucleic acid complex and nucleic acid delivery composition | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-12-25 | — | — | US | disclosed |
| EP-2405001-A1 | NUCLEIC ACID COMPLEX AND NUCLEIC ACID-DELIVERING COMPOSITION | Takeuchi, Hirofumi (JP) | 2012-01-11 | — | — | EP | disclosed |
| US-8030075-B2 | Carrier composition for nucleic acid transport | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2011-10-04 | — | — | US | disclosed |
| EP-2217208-B1 | NUCLEIC ACID COMPLEX AND NUCLEIC ACID DELIVERY COMPOSITION | OTSUKA PHARMA CO LTD (JP) | 2011-08-31 | — | — | EP | disclosed |
| US-20100305190-A1 | NUCLEIC ACID COMPLEX AND NUCLEIC ACID DELIVERY COMPOSITION | Takeuchi, Hirofumi (JP) | 2010-12-02 | — | — | US | disclosed |
| EP-2217208-A2 | NUCLEIC ACID COMPLEX AND NUCLEIC ACID DELIVERY COMPOSITION | Otsuka Pharmaceutical Co., Ltd. (JP) | 2010-08-18 | — | — | EP | disclosed |
| US-20100063131-A1 | PROMPT NUCLEIC ACID DELIVERY CARRIER COMPOSITION | Takeuchi, Hirofumi (JP) | 2010-03-11 | — | — | US | disclosed |
| EP-2140870-A1 | PROMPT NUCLEIC ACID DELIVERY CARRIER COMPOSITION | Otsuka Pharmaceutical Co., Ltd. (JP) | 2010-01-06 | — | — | EP | disclosed |
| US-20090258923-A1 | Carrier Composition for Nucleic Acid Transport | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-10-15 | — | — | US | disclosed |
| WO-2009061003-A2 | NUCLEIC ACID COMPLEX AND NUCLEIC ACID DELIVERY COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-05-14 | — | — | WO | disclosed |
| EP-1946761-A1 | CARRIER COMPOSITION FOR NUCLEIC ACID TRANSPORT | Otsuka Pharmaceutical Co., Ltd. (JP) | 2008-07-23 | — | — | EP | disclosed |