Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 14/20 | 0.47 |
| ▸ | TACR2 | P21452 | 13/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4667076 | 0.91 | LMNA (0.48) | TACR3TACR2OPRM1LMNATRPV4 | |
| SCHEMBL4665926 | 0.91 | LMNA (0.48) | TACR3TACR2OPRM1LMNATRPV4 | |
| SCHEMBL4665219 | 0.88 | TACR3 (0.47) | TACR3TACR2OPRM1LMNAKCNH2 | |
| SCHEMBL4665275 | 0.85 | LMNA (0.64) | TACR3TACR2LMNAKCNH2 | |
| SCHEMBL4665243 | 0.84 | LMNA (0.57) | TACR3TACR2LMNAKCNH2 | |
| SCHEMBL4665898 | 0.83 | TACR2 (0.65) | TACR3TACR2OPRM1TRPV4 | |
| SCHEMBL4668628 | 0.80 | LMNA (0.49) | TACR3TACR2OPRM1LMNAKCNH2 | |
| SCHEMBL6625208 | 0.80 | LMNA (0.53) | TACR3TACR2OPRM1LMNATRPV4 | |
| SCHEMBL6626579 | 0.79 | ALDH1A1 (0.56) | TACR3TACR2OPRM1LMNA | |
| SCHEMBL4665874 | 0.79 | TACR3 (0.61) | TACR3TACR2TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940795-A1 | N-OXO-HETEROCYCLE AND N-OXO-ALKYL QUINOLINE-4-CARBOXAMIDES AS NK-3 RECEPTOR LIGANDS | AstraZeneca AB (SE) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007035156-A1 | N-OXO-HETEROCYCLE AND N-OXO-ALKYL QUINOLINE-4-CARBOXAMIDES AS NK-3 RECEPTOR LIGANDS | ASTRAZENECA AB (SE) | 2007-03-29 | — | — | WO | disclosed |