Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4668038 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL4668704 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KDM4EGLAMAPTSMN1; SMN2 | |
| SCHEMBL18033022 | 0.77 | CA12 (0.56) | MAPTRAB9ATSHRHTT | |
| SCHEMBL2434485 | 0.76 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL4667302 | 0.72 | ALDH1A1 (0.49) | ALDH1A1KDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL9499966 | 0.72 | GAA (0.47) | ALDH1A1KDM4EGLAMAPTNPC1 | |
| SCHEMBL13181209 | 0.71 | TNF (0.42) | ALDH1A1KDM4EGLATDP1TSHR | |
| SCHEMBL4668742 | 0.71 | RORC (0.39) | ALDH1A1KDM4EGLAMAPTNPC1 | |
| SCHEMBL454595 | 0.70 | TNF (0.44) | ALDH1A1KDM4EGLAMAPTTDP1 | |
| SCHEMBL7274350 | 0.70 | ALOX5 (0.48) | MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129689-B1 | Keratinous fiber dyeing composition comprising N-(2-hydroxybenzene)-carbamate or N-(2-hydroxybenzene)urea derivatives as coupling agents and process for dyeing | OREAL (FR) | 2008-07-09 | — | — | EP | claimed |