Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4667161 | 0.88 | ESR1 (0.53) | PTPN1PTPN6PTPN11ESR1SMN1; SMN2 | |
| SCHEMBL4667240 | 0.83 | PTPN1 (0.61) | PTPN1PTPN6PTPN11SMN1; SMN2ALDH1A1 | |
| SCHEMBL4667289 | 0.81 | STS (0.54) | PTPN1PTPN6PTPN11APLNRLMNA | |
| SCHEMBL31201812 | 0.80 | ESR1 (0.65) | PTPN1PTPN6PTPN11ESR1ALDH1A1 | |
| SCHEMBL2000447 | 0.78 | ALDH1A1 (0.52) | ESR1ALDH1A1LMNAGAAMEN1 | |
| SCHEMBL27577463 | 0.76 | STS (0.49) | PTPN1PTPN6PTPN11APLNRLMNA | |
| SCHEMBL10561547 | 0.76 | GRM2 (0.60) | SMN1; SMN2LMNAGAAMEN1KMT2A | |
| Hydrogen Sulfide SCHEMBL27743268 | 0.76 | ALDH1A1 (0.50) | ESR1ALDH1A1LMNAGAAMEN1 | |
| SCHEMBL8888489 | 0.73 | ACHE (0.57) | PTPN1PTPN6PTPN11APLNRSMN1; SMN2 | |
| SCHEMBL5863689 | 0.73 | NR3C1 (0.68) | PTPN1ESR1ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193250-B1 | PHENYL SULFAMATE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |