SCHEMBL4773148

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4775349	0.83	LMNA (0.41)	ALDH1A1SMN1; SMN2LMNAPTPN1NR1H4
	SCHEMBL4777413	0.83	KDM4E (0.52)	ALDH1A1LMNAPOLBHPGDPGR
	SCHEMBL4775267	0.83	ALDH1A1 (0.52)	ALDH1A1SMN1; SMN2LMNANPC1HPGD
	SCHEMBL4773540	0.82	GAA (0.43)	ALDH1A1SMN1; SMN2LMNANR1H4POLB
	SCHEMBL4771201	0.80	LMNA (0.50)	ALDH1A1SMN1; SMN2LMNAPOLBMMP2
	SCHEMBL4769790	0.80	KDM4E (0.44)	ALDH1A1SMN1; SMN2LMNANR1H4POLB
	SCHEMBL4772377	0.79	PNMT (0.47)	ALDH1A1SMN1; SMN2LMNAPTPN1POLB
	SCHEMBL4777553	0.79	ALDH1A1 (0.49)	ALDH1A1SMN1; SMN2LMNAPOLBGAA
	SCHEMBL4777644	0.78	GAA (0.45)	ALDH1A1SMN1; SMN2LMNAPTPN1NR1H4
	SCHEMBL4772365	0.78	GAA (0.50)	ALDH1A1SMN1; SMN2LMNANR1H4GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.