Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 6/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.81 |
| ▸ | MAPT | P10636 | 5/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.81 |
| ▸ | CLK1 | P49759 | 4/20 | 0.81 |
| ▸ | HPGD | P15428 | 4/20 | 0.81 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.81 |
| ▸ | CLK3 | P49761 | 3/20 | 0.81 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.81 |
| ▸ | HTT | P42858 | 3/20 | 0.81 |
| ▸ | PIM1 | P11309 | 2/20 | 0.81 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.81 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.81 |
| ▸ | MAP3K19 | Q56UN5 | 2/20 | 0.81 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.81 |
| ▸ | CSNK1G3 | Q9Y6M4 | 2/20 | 0.81 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.81 |
| ▸ | CLK2 | P49760 | 2/20 | 0.81 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.81 |
| ▸ | MEN1 | O00255 | 2/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166902 | 1.00 | DYRK1A (0.81) | DYRK1AHSD17B10MAPTALDH1A1CLK1 | |
| SCHEMBL4667255 | 1.00 | DYRK1A (0.81) | DYRK1AHSD17B10MAPTALDH1A1CLK1 | |
| SCHEMBL2977826 | 0.90 | DYRK1A (1.00) | DYRK1AHSD17B10MAPTALDH1A1CLK1 | |
| SCHEMBL2977830 | 0.90 | DYRK1A (1.00) | DYRK1AHSD17B10MAPTALDH1A1CLK1 | |
| SCHEMBL18416400 | 0.83 | CLK1 (0.64) | DYRK1AHSD17B10MAPTALDH1A1CLK1 | |
| SCHEMBL14306939 | 0.81 | MAPT (0.54) | DYRK1AHSD17B10MAPTALDH1A1CLK1 | |
| SCHEMBL14281090 | 0.79 | MAPT (0.52) | DYRK1AHSD17B10MAPTALDH1A1CLK1 | |
| SCHEMBL19897109 | 0.79 | SNCA (0.55) | DYRK1AHSD17B10MAPTALDH1A1CLK1 | |
| SCHEMBL24718937 | 0.79 | MAPT (1.00) | DYRK1AHSD17B10MAPTALDH1A1CLK1 | |
| SCHEMBL4018924 | 0.79 | DYRK1A (0.80) | DYRK1AHSD17B10MAPTALDH1A1CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230372309-A1 | ALPHA-2 ADRENERGIC RECEPTOR ANTAGONIST | KYOTO UNIVERSITY (JP) | 2023-11-23 | — | — | US | disclosed |
| EP-4218818-A1 | ALPHA-2 ADRENERGIC RECEPTOR ANTAGONIST | Kyoto University (JP) | 2023-08-02 | — | — | EP | disclosed |
| EP-3085698-B1 | PAIN-RELATED COMPOUND AND MEDICINAL COMPOSITION | UNIV KYOTO (JP) | 2019-11-13 | — | — | EP | disclosed |
| US-9745275-B2 | Pain-related compound and medical composition | KYOTO UNIVERSITY (JP) | 2017-08-29 | — | — | US | disclosed |
| US-20170029389-A1 | PAIN-RELATED COMPOUND AND MEDICAL COMPOSITION | KYOTO UNIVERSITY (JP) | 2017-02-02 | — | — | US | disclosed |
| EP-3085698-A1 | PAIN-RELATED COMPOUND AND MEDICINAL COMPOSITION | Kyoto University (JP) | 2016-10-26 | — | — | EP | disclosed |
| US-20080193700-A1 | Metal Chelates and Their Use in Optical Recording Media Having High Storage Capacity | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2008-08-14 | — | — | US | disclosed |
| EP-1743333-A1 | METAL CHELATES AND THEIR USE IN OPTICAL RECORDING MEDIA HAVING HIGH STORAGE CAPACITY | CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005106868-A1 | METAL CHELATES AND THEIR USE IN OPTICAL RECORDING MEDIA HAVING HIGH STORAGE CAPACITY | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2005-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230372309-A1 | ALPHA-2 ADRENERGIC RECEPTOR ANTAGONIST | ADRA2A, ADRB2, ADRA2B | DYRK1A 910/4885HSD17B10 2460/4885MAPT 2183/4885 |
| US-20170029389-A1 | PAIN-RELATED COMPOUND AND MEDICAL COMPOSITION | OPRL1, TRPV1, P2RY11 | DYRK1A 2941/4885HSD17B10 1797/4885MAPT 672/4885 |
| US-20080193700-A1 | Metal Chelates and Their Use in Optical Recording Media Having High Storage Capacity | TMCO1, KCNN3, CACNA1F | DYRK1A 4133/4885HSD17B10 4629/4885MAPT 580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.