Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 6/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4665424 | 0.86 | CCR5 (0.38) | OPRK1OPRD1OPRM1CYP2C9CYP2C19 | |
| SCHEMBL4663500 | 0.83 | OPRM1 (0.42) | OPRK1OPRD1OPRM1LMNAGAA | |
| SCHEMBL4664230 | 0.83 | SCN9A (0.39) | OPRK1OPRD1OPRM1CYP2C9CYP2C19 | |
| SCHEMBL4663488 | 0.83 | OPRK1 (0.38) | OPRK1OPRD1OPRM1SMN1; SMN2TDP1 | |
| SCHEMBL4664046 | 0.82 | SMN1; SMN2 (0.48) | OPRK1OPRD1OPRM1SMN1; SMN2TDP1 | |
| SCHEMBL4667278 | 0.82 | LMNA (0.53) | OPRK1TRPA1OPRD1OPRM1LMNA | |
| SCHEMBL4665379 | 0.81 | OPRK1 (0.42) | OPRK1OPRD1OPRM1LMNAGAA | |
| SCHEMBL4664196 | 0.81 | OPRK1 (0.47) | OPRK1OPRD1OPRM1LMNAGAA | |
| SCHEMBL4663483 | 0.79 | DRD2 (0.41) | OPRK1TRPA1OPRD1OPRM1HTR2B | |
| SCHEMBL4665354 | 0.79 | DRD2 (0.41) | OPRK1TRPA1OPRD1OPRM1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1571140-B1 | C-substituted cyclohexylmethylamine derivatives | GRUENENTHAL GMBH (DE) | 2008-11-12 | — | — | EP | claimed |