Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.55 |
| ▸ | NOS1 | P29475 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | STAT1 | P42224 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13851927 | 0.89 | TSHR (0.69) | NOS3NOS1MAPTRAB9AMAPK1 | |
| SCHEMBL8724560 | 0.88 | HPGD (0.48) | NOS3NOS1MAPTRAB9AMAPK1 | |
| SCHEMBL8093579 | 0.88 | MAPT (0.46) | NOS3NOS1MAPTRAB9AMAPK1 | |
| SCHEMBL11796884 | 0.84 | CYP3A4 (0.50) | NOS3NOS1MAPTRAB9AMAPK1 | |
| SCHEMBL31650976 | 0.82 | CYP3A4 (0.52) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL308386 | 0.82 | CYP3A4 (0.52) | NOS3NOS1MAPTMAPK1TDP1 | |
| SCHEMBL4935768 | 0.81 | CYP3A4 (0.47) | NOS3NOS1MAPTRAB9AMAPK1 | |
| SCHEMBL1308638 | 0.81 | NOS3 (0.53) | NOS3NOS1MAPTRAB9AMAPK1 | |
| Ethane SCHEMBL4422870 | 0.81 | TSHR (0.50) | NOS1NPC1SMN1; SMN2CYP3A4TSHR | |
| SCHEMBL1878165 | 0.80 | TSHR (0.55) | MAPTNPC1SMN1; SMN2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 470 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12528777-B2 | Quinazolinones derivatives for treatment of non-alcoholic fatty liver disease, preparation and use thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2026-01-20 | — | — | US | claimed |
| EP-4480947-A1 | PREPARATION METHOD AND USE OF NOVEL TAXANE COMPOUND | Jiangsu Jibeier Pharmaceutical Co. Ltd. (CN) | 2024-12-25 | — | — | EP | claimed |
| CN-118813018-A | Method for manufacturing biodegradable plastic | 河北雄安骅洋纸塑包装实业有限公司 | 2024-10-22 | — | — | CN | claimed |
| CN-118791447-A | Preparation method and application of novel taxane compound | 江苏吉贝尔药业股份有限公司 | 2024-10-18 | — | — | CN | claimed |
| WO-2024212430-A1 | PREPARATION METHOD AND USE OF NOVEL TAXANE COMPOUND | 江苏吉贝尔药业股份有限公司 | 2024-10-17 | — | — | WO | claimed |
| US-20230357165-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-11-09 | — | — | US | claimed |
| CN-111471171-B | Arylsulfonic acid intermediate, preparation method thereof and application of aryl sulfonic acid intermediate in synthesizing low-temperature-sensitivity additive for concrete | 江苏苏博特新材料股份有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-116375668-A | Preparation method and application of novel taxane compound | 江苏吉贝尔药业股份有限公司 | 2023-07-04 | — | — | CN | claimed |
| CN-115385973-B | Application of oligonucleotide-tetrahydrothiazole compounds in synthesis of gene coding compound library | 康龙化成(宁波)科技发展有限公司 | 2023-06-06 | — | — | CN | claimed |
| EP-4171569-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | Council of Scientific & Industrial Research (IN) | 2023-05-03 | — | — | EP | claimed |
| CN-116042168-A | High-viscosity quick UV (ultraviolet) curing adhesive and preparation method thereof | 安徽大学 | 2023-05-02 | — | — | CN | claimed |
| CN-115385973-A | Application of oligo-nucleic acid-thiazolidine compound in synthesis of gene coding compound library | 康龙化成(宁波)科技发展有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-112349449-B | Transparent conductive coating and preparation method and application thereof | 中国建筑材料科学研究总院有限公司 | 2022-04-08 | — | — | CN | claimed |
| CN-111910946-B | Construction method of concrete roof water leakage repairing system | 厦门顶巢建筑修缮研究院有限公司 | 2022-04-05 | — | — | CN | claimed |
| WO-2022003712-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2022-01-06 | — | — | WO | claimed |
| CN-112349449-A | Transparent conductive coating and preparation method and application thereof | 中国建筑材料科学研究总院有限公司 | 2021-02-09 | — | — | CN | claimed |
| CN-111910946-A | Construction method of concrete roof water leakage repairing system | 厦门顶巢建筑修缮研究院有限公司 | 2020-11-10 | — | — | CN | claimed |
| CN-111471171-A | Aryl sulfonic acid intermediate, preparation method thereof and application thereof in synthesizing low-temperature-sensitivity additive for concrete | 江苏苏博特新材料股份有限公司 | 2020-07-31 | — | — | CN | claimed |
| US-20120012796-A1 | CONDUCTIVE FILMS BASED ON GRAPHENE AND PROCESS FOR PREPARING THE SAME | NANKAI UNIVERSITY (CN) | 2012-01-19 | — | — | US | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357165-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | ATG7, GOT1, LIPC | NOS3 2076/4885NOS1 1186/4885MAPT 2243/4885 |
| US-12528777-B2 | Quinazolinones derivatives for treatment of non-alcoholic fatty liver disease, preparation and use thereof | ATG7, GOT1, ULK1 | NOS3 1595/4885NOS1 1505/4885MAPT 2743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.