Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.52 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8140554 | 0.87 | VCAM1 (0.60) | XDHVCAM1APPALDH1A1LMNA | |
| SCHEMBL9373575 | 0.84 | VCAM1 (0.54) | VCAM1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL30676035 | 0.84 | MAPT (0.51) | XDHVCAM1ALDH1A1LMNAMAPT | |
| SCHEMBL26926327 | 0.84 | MAPT (0.51) | XDHVCAM1ALDH1A1LMNAMAPT | |
| SCHEMBL30676063 | 0.83 | CYP11B1 (0.49) | VCAM1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL26926329 | 0.83 | CYP11B1 (0.49) | VCAM1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL4667754 | 0.82 | STS (0.67) | VCAM1ALDH1A1LMNA | |
| SCHEMBL26926237 | 0.82 | LMNA (0.47) | XDHVCAM1ALDH1A1LMNAMAPT | |
| SCHEMBL6800482 | 0.81 | LMNA (0.47) | XDHVCAM1ALDH1A1LMNAHTT | |
| SCHEMBL4667310 | 0.81 | VCAM1 (0.54) | XDHVCAM1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193250-B1 | PHENYL SULFAMATE DERIVATIVES | TEIKOKU HORMONE MFG CO LTD (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |