Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28883135 | 0.91 | MAOA (0.44) | ALDH1A1KDM4ECYP3A4TDP1L3MBTL1 | |
| SCHEMBL28958670 | 0.85 | CYP3A4 (0.54) | ALDH1A1KDM4ECYP3A4TDP1L3MBTL1 | |
| SCHEMBL29375628 | 0.78 | CYP3A4 (0.42) | ALDH1A1KDM4ECYP3A4TDP1L3MBTL1 | |
| SCHEMBL94021 | 0.78 | CYP3A4 (0.42) | ALDH1A1KDM4ECYP3A4TDP1L3MBTL1 | |
| SCHEMBL891571 | 0.74 | KDM4E (0.39) | ALDH1A1KDM4ECYP3A4TDP1L3MBTL1 | |
| SCHEMBL29825453 | 0.74 | MAOA (0.44) | ALDH1A1KDM4ECYP3A4TDP1L3MBTL1 | |
| SCHEMBL18604654 | 0.74 | MAOA (0.44) | ALDH1A1KDM4ECYP3A4TDP1L3MBTL1 | |
| SCHEMBL18979892 | 0.73 | CYP3A4 (0.62) | ALDH1A1KDM4ECYP3A4TDP1L3MBTL1 | |
| SCHEMBL453394 | 0.72 | KDM4E (0.55) | KDM4ECYP3A4TDP1L3MBTL1CYP2C9 | |
| SCHEMBL3725884 | 0.72 | ALDH1A1 (0.49) | ALDH1A1KDM4ECYP3A4TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1982748-A2 | Novel hair colouring compositions for use in oxidative hair dyeing | The Procter & Gamble (US) | 2008-10-22 | — | — | EP | claimed |
| CN-101137345-A | Novel hair coloring compositions for oxidative hair dyeing | PROCTER & GAMBLE (US) | 2008-03-05 | — | — | CN | claimed |
| US-7303592-B2 | Hair coloring compositions for use in oxidative hair dyeing | THE PROCTER & GAMBLE COMPANY (US) | 2007-12-04 | — | — | US | claimed |
| EP-1855644-A2 | HAIR COLORING COMPOSITIONS FOR USE IN OXIDATIVE HAIR DYEING | The Procter and Gamble Company (US) | 2007-11-21 | — | — | EP | claimed |
| WO-2006099115-A2 | HAIR COLORING COMPOSITIONS FOR USE IN OXIDATIVE HAIR DYEING | THE PROCTER & GAMBLE COMPANY (US) | 2006-09-21 | — | — | WO | claimed |
| US-20050188480-A1 | Novel hair coloring compositions for use in oxidative hair dyeing | WELLA OPERATIONS US, LLC | 2005-09-01 | — | — | US | claimed |
| CN-101137345-B | Novel hair coloring compositions for oxidative hair dyeing | PROCTER & GAMBLE | 2012-10-31 | — | — | CN | disclosed |
| EP-1982749-A2 | Novel hair colouring compositions for use in oxidative hair dyeing | The Procter and Gamble Company (US) | 2008-10-22 | — | — | EP | disclosed |
| EP-1982748-A2 | Novel hair colouring compositions for use in oxidative hair dyeing | The Procter & Gamble (US) | 2008-10-22 | — | — | EP | disclosed |
| CN-101137345-A | Novel hair coloring compositions for oxidative hair dyeing | PROCTER & GAMBLE (US) | 2008-03-05 | — | — | CN | disclosed |
| US-7303592-B2 | Hair coloring compositions for use in oxidative hair dyeing | THE PROCTER & GAMBLE COMPANY (US) | 2007-12-04 | — | — | US | disclosed |
| EP-1855644-A2 | HAIR COLORING COMPOSITIONS FOR USE IN OXIDATIVE HAIR DYEING | The Procter and Gamble Company (US) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006099115-A2 | HAIR COLORING COMPOSITIONS FOR USE IN OXIDATIVE HAIR DYEING | THE PROCTER & GAMBLE COMPANY (US) | 2006-09-21 | — | — | WO | disclosed |
| US-20050188480-A1 | Novel hair coloring compositions for use in oxidative hair dyeing | WELLA OPERATIONS US, LLC | 2005-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050188480-A1 | Novel hair coloring compositions for use in oxidative hair dyeing | COXFA4L2, TYR, GPX4 | ALDH1A1 89/4885KDM4E 2480/4885CYP3A4 310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.