Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2974731 | 0.89 | MAPT (0.37) | KDM4ECYP3A4ALDH1A1TDP1TSHR | |
| SCHEMBL28958670 | 0.80 | CYP3A4 (0.54) | KDM4ECYP3A4ALDH1A1TDP1TSHR | |
| SCHEMBL1982306 | 0.77 | KDM4E (0.69) | KDM4ECYP3A4ALDH1A1TDP1TSHR | |
| SCHEMBL4667347 | 0.74 | ALDH1A1 (0.38) | KDM4ECYP3A4ALDH1A1TDP1TSHR | |
| SCHEMBL18979892 | 0.74 | CYP3A4 (0.62) | KDM4ECYP3A4ALDH1A1TDP1TSHR | |
| SCHEMBL8521178 | 0.74 | ALDH1A1 (0.54) | KDM4ECYP3A4ALDH1A1TDP1TSHR | |
| SCHEMBL33874 | 0.74 | ALDH1A1 (0.54) | KDM4ECYP3A4ALDH1A1TDP1TSHR | |
| SCHEMBL7257009 | 0.73 | L3MBTL1 (0.36) | KDM4ECYP3A4ALDH1A1TDP1TSHR | |
| SCHEMBL33796 | 0.72 | ALDH1A1 (0.52) | KDM4ECYP3A4ALDH1A1TDP1TSHR | |
| Water SCHEMBL3359653 | 0.72 | ALDH1A1 (0.52) | KDM4ECYP3A4ALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6638321-B1 | Oxidation color dyes for hair from aniline compounds | L'OREAL (FR) | 2003-10-28 | — | — | US | claimed |
| US-20010020310-A1 | Compositions for dyeing keratinous fibres, containing 3-aminopyrazolo[1,5-a]pyrimidines, method of dyeing, and novel 3-aminopyrazolo[1,5-a]pyrimidines | L'OREAL S.A. | 2001-09-13 | — | — | US | claimed |
| US-20210346258-A1 | DHA AS A HAIR COLOURANT | Vivimed Specialty Chemicals UK Limited (GB) | 2021-11-11 | — | — | US | disclosed |
| US-20150315177-A1 | SUBSTITUTED QUINONES OR ANALOGUES AS COLOURING AGENTS | MERCK PATENT GMBH (DE) | 2015-11-05 | — | — | US | disclosed |
| US-8349023-B2 | After treatment for color fixation | HENKEL AG & CO. KGAA (DE) | 2013-01-08 | — | — | US | disclosed |
| US-20120080046-A1 | After Treatment for Color Fixation | HENKEL AG & CO. KGAA (DE) | 2012-04-05 | — | — | US | disclosed |
| EP-1562538-B1 | COSMETIC COMPOSITION COMPRISING AT LEAST ONE SPECIFIC CYCLIC CARBONATE WHICH MAY BE POLYMERISED | OREAL (FR) | 2010-11-03 | — | — | EP | disclosed |
| US-7132543-B2 | Para-phenylenediamine derivatives containing a disubstituted pyrrolidinyl group bearing a cationic radical, and use of the same for dyeing keratin fibers | L'OREAL S.A. (FR) | 2006-11-07 | — | — | US | disclosed |
| US-20040248961-A1 | Para-phenylenediamine derivatives containing a disubstituted pyrrolidinyl group bearing a cationic radical, and use of the same for dyeing keratin fibers | L'OREAL S.A. (FR) | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150315177-A1 | SUBSTITUTED QUINONES OR ANALOGUES AS COLOURING AGENTS | KRT18, IK, SDHA | KDM4E 763/4885CYP3A4 2614/4885ALDH1A1 264/4885 |
| US-20010020310-A1 | Compositions for dyeing keratinous fibres, containing 3-aminopyrazolo[1,5-a]pyrimidines, method of dyeing, and novel 3-aminopyrazolo[1,5-a]pyrimidines | DPYD, KRT18, PNPO | KDM4E 836/4885CYP3A4 940/4885ALDH1A1 443/4885 |
| US-20040248961-A1 | Para-phenylenediamine derivatives containing a disubstituted pyrrolidinyl group bearing a cationic radical, and use of the same for dyeing keratin fibers | KRT18, CDC73, PKN1 | KDM4E 1264/4885CYP3A4 1895/4885ALDH1A1 783/4885 |
| US-20120080046-A1 | After Treatment for Color Fixation | TYR, NAT1, KAT2A | KDM4E 1271/4885CYP3A4 794/4885ALDH1A1 376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.