Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4664665 | 0.85 | TGFBR1 (0.40) | KCNMA1ALDH1A1HPGDTGFBR1TP53 | |
| SCHEMBL4665548 | 0.83 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL27749269 | 0.83 | TP53 (0.43) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL27749272 | 0.82 | TP53 (0.42) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL4668860 | 0.79 | KCNMA1 (0.38) | KCNMA1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL14600443 | 0.75 | MAPK14 (0.53) | — | |
| SCHEMBL14600709 | 0.73 | MARS1 (0.43) | ALDH1A1KMT2AMEN1KDM4ECYP1A2 | |
| SCHEMBL27728861 | 0.70 | KMT2A (0.51) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL15712337 | 0.69 | KCNMA1 (0.41) | KCNMA1KMT2AMEN1HPGDTGFBR1 | |
| SCHEMBL14600228 | 0.69 | HPGD (0.38) | ALDH1A1KMT2AMEN1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928455-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | Bayer Healthcare, LLC (US) | 2008-06-11 | — | — | EP | disclosed |
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |
| WO-2007027842-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER HEALTHCARE LLC (US) | 2007-03-08 | — | — | WO | disclosed |