Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.37 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.36 |
| ▸ | CDK2 | P24941 | 3/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4712786 | 0.83 | DDB1 (0.56) | EIF2AK2DDB1CRBNALDH1A1POLB | |
| SCHEMBL305860 | 0.83 | ALDH1A1 (0.55) | EIF2AK2DDB1CRBNALDH1A1POLB | |
| SCHEMBL3858961 | 0.82 | EIF2AK2 (0.39) | EIF2AK2DDB1CRBNALDH1A1POLB | |
| SCHEMBL2723456 | 0.82 | HTR3E (0.47) | EIF2AK2ALDH1A1POLBITGB3ITGB1 | |
| SCHEMBL2199529 | 0.82 | KMT2A (0.41) | EIF2AK2DDB1CRBNALDH1A1POLB | |
| SCHEMBL2883318 | 0.82 | ADRB1 (0.47) | POLBSMN1; SMN2CMA1MEN1KMT2A | |
| SCHEMBL4626160 | 0.82 | FAAH (0.41) | EIF2AK2DDB1CRBNALDH1A1POLB | |
| SCHEMBL4056377 | 0.82 | GLA (0.41) | EIF2AK2DDB1CRBNALDH1A1POLB | |
| SCHEMBL19604817 | 0.82 | EIF2AK2 (0.39) | EIF2AK2DDB1CRBNALDH1A1POLB | |
| SCHEMBL12068144 | 0.82 | EIF2AK2 (0.39) | EIF2AK2DDB1CRBNALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654254-A4 | ANTIFUNGAL AZOLE DERIVATIVES HAVING A FLUOROVINYL MOIETY AND PROCESS FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2008-12-31 | — | — | EP | disclosed |
| US-20080027117-A1 | Antifungal Azole Derivatives Having a Fluorovinyl Moiety and Process for the Preparation Thereof | KOREA RESERACH INSTIITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-01-31 | — | — | US | disclosed |
| EP-1654254-A1 | ANTIFUNGAL AZOLE DERIVATIVES HAVING A FLUOROVINYL MOIETY AND PROCESS FOR THE PREPARATION THEREOF | Korea Research Institute of Chemical Technology (KR) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005014583-A1 | ANTIFUNGAL AZOLE DERIVATIVES HAVING A FLUOROVINYL MOIETY AND PROCESS FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027117-A1 | Antifungal Azole Derivatives Having a Fluorovinyl Moiety and Process for the Preparation Thereof | ERG28, CYP51A1, CYP4F8 | EIF2AK2 1480/4885DDB1 2458/4885CRBN 492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.