SCHEMBL466830

SCHEMBL466830

CCO[Si](CCCc1cccc2sc(SSSSc3nc4c(CCC[Si](OCC)(OCC)OCC)cccc4s3)nc12)(OCC)OCC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 2/20 0.37
PTGS2 P35354 1/20 0.37
ALDH1A1 P00352 4/20 0.33
LMNA P02545 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
POLB P06746 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
KDM4E B2RXH2 2/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
MAPK1 P28482 1/20 0.32
ADRA2A P08913 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
DRD2 P14416 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28492615 0.95 PTGS2 (0.35) FBP1PTGS2ALDH1A1LMNASMN1; SMN2
SCHEMBL329562 0.88 PTGS2 (0.38) FBP1PTGS2ALDH1A1MEN1KMT2A
SCHEMBL8827120 0.82 FBP1 (0.49) FBP1PTGS2ALDH1A1LMNASMN1; SMN2
SCHEMBL330194 0.81 PTGS2 (0.35) FBP1PTGS2ALDH1A1MEN1KMT2A
SCHEMBL8826349 0.81 FBP1 (0.48) FBP1PTGS2ALDH1A1LMNASMN1; SMN2
SCHEMBL8826810 0.81 FBP1 (0.48) FBP1PTGS2ALDH1A1LMNASMN1; SMN2
SCHEMBL8826904 0.81 FBP1 (0.48) FBP1PTGS2ALDH1A1LMNASMN1; SMN2
SCHEMBL8826772 0.81 FBP1 (0.48) FBP1PTGS2ALDH1A1LMNASMN1; SMN2
SCHEMBL8826876 0.80 FBP1 (0.49) FBP1PTGS2ALDH1A1LMNASMN1; SMN2
SCHEMBL8826716 0.78 FBP1 (0.45) FBP1PTGS2ALDH1A1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110199187-B Method for predicting rubber reinforcing effect of organic-inorganic composite material for rubber reinforcement 株式会社LG化学 2022-02-11 CN claimed
CN-110191917-B Organic-inorganic composite material for rubber reinforcement, method for preparing the same, and rubber composition for tire comprising the same 株式会社LG化学 2021-05-25 CN claimed
EP-4438340-B1 TIRE WITH IMPROVED RUBBER COMPOUND BRIDGESTONE EUROPE NV SA (BE) 2026-05-27 EP disclosed
EP-4703425-A1 TIRE RUBBER COMPOSITION, TREAD RUBBER, AND TIRE BRIDGESTONE CORPORATION (JP) 2026-03-04 EP disclosed
US-20260055262-A1 RUBBER COMPOSITION FOR TIRES YOKOHAMA RUBBER CO LTD (JP) 2026-02-26 US disclosed
EP-4349614-B1 RUBBER COMPOSITION FOR TIRE, TREAD RUBBER, AND TIRE BRIDGESTONE CORP (JP) 2026-02-25 EP disclosed
EP-4349615-B1 RUBBER COMPOSITION FOR TIRE, TREAD RUBBER, AND TIRE BRIDGESTONE CORP (JP) 2026-02-18 EP disclosed
EP-4691799-A1 TWO-WHEEL VEHICLE TIRE BRIDGESTONE CORPORATION (JP) 2026-02-11 EP disclosed
US-20260035547-A1 RUBBER COMPOSITION YOKOHAMA RUBBER CO LTD (JP) 2026-02-05 US disclosed
WO-2025262619-A1 RUBBER COMPOSITIONS BRIDGESTONE CORPORATION (JP) 2025-12-26 WO disclosed
EP-4667236-A1 RUBBER COMPOSITIONS BRIDGESTONE CORPORATION (JP) 2025-12-24 EP disclosed
US-7045567-B2 Rubber composition for tire tread and pneumatic tire using the rubber composition SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2006-05-16 US disclosed
US-20050187332-A1 Rubber composition SUMITOMO RUBBER INDUSTRIES, LTD. 2005-08-25 US disclosed
EP-1566404-A1 Rubber composition SUMITOMO RUBBER INDUSTRIES LTD. (JP) 2005-08-24 EP disclosed
US-20050159554-A1 Process for producing modified polymer, modified polymer obtained by the process, and rubber composition BRIDGESTONE CORPORATION (JP) 2005-07-21 US disclosed
EP-1505113-A1 Rubber composition for tire tread and pneumatic tire using the rubber composition Sumitomo Rubber Industries Ltd. (JP) 2005-02-09 EP disclosed
EP-1505087-A1 PROCESS FOR PRODUCING MODIFIED POLYMER, MODIFIED POLYMER OBTAINED BY THE PROCESS, AND RUBBER COMPOSITION Bridgestone Corporation (JP) 2005-02-09 EP disclosed
US-20050027060-A1 Rubber composition for tire tread and pneumatic tire using the rubber composition SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2005-02-03 US disclosed
US-20050020757-A1 Process for producing modified polymer modified polymer obtained by the process and rubber composition BRIDGESTONE CORPORATION (JP) 2005-01-27 US disclosed
EP-1462459-A1 PROCESS FOR PRODUCING MODIFIED POLYMER, MODIFIED POLYMER OBTAINED BY THE PROCESS, AND RUBBER COMPOSITION Bridgestone Corporation (JP) 2004-09-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035547-A1 RUBBER COMPOSITION LBR, TAF1, CCT4 FBP1 1081/4885PTGS2 267/4885ALDH1A1 1998/4885
US-20260055262-A1 RUBBER COMPOSITION FOR TIRES TRRAP, RAD51, TERT FBP1 2282/4885PTGS2 722/4885ALDH1A1 2033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.