SCHEMBL330194

SCHEMBL330194

CO[Si](C)(CCCc1cccc2sc(SSSSc3nc4c(CCC[Si](C)(OC)OC)cccc4s3)nc12)OC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.35
ALDH1A1 P00352 3/20 0.33
FBP1 P09467 2/20 0.33
TDP1 Q9NUW8 2/20 0.32
PDK1 Q15118 2/20 0.32
ADRA2A P08913 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
DRD2 P14416 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
DRD1 P21728 1/20 0.32
MC5R P33032 1/20 0.32
OPRM1 P35372 1/20 0.32
DRD3 P35462 1/20 0.32
OPRK1 P41145 1/20 0.32
CCR2 P41597 1/20 0.32
HTR6 P50406 1/20 0.32
SLC6A3 Q01959 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL329562 0.89 PTGS2 (0.38) PTGS2ALDH1A1FBP1TDP1PDK1
SCHEMBL466830 0.81 FBP1 (0.37) PTGS2ALDH1A1FBP1TDP1PDK1
SCHEMBL330195 0.79 PTGS2 (0.33) PTGS2FBP1
SCHEMBL11324676 0.78 PTGS2 (0.39) PTGS2ALDH1A1TDP1HPGDCYP3A4
SCHEMBL28492615 0.78 PTGS2 (0.35) PTGS2ALDH1A1FBP1
SCHEMBL17625872 0.77 ALDH1A1 (0.33) ALDH1A1FBP1TDP1PDK1ADRA2A
SCHEMBL16040592 0.75 FBP1 (0.33) ALDH1A1FBP1TDP1PDK1ADRA2A
SCHEMBL6694867 0.74 ALDH1A1 (0.43) PTGS2ALDH1A1FBP1TDP1PDK1
SCHEMBL3278496 0.73 FBP1 (0.51) ALDH1A1FBP1TDP1PDK1ADRA2A
SCHEMBL8826393 0.72 FBP1 (0.50) ALDH1A1FBP1TDP1PDK1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 452 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4438340-B1 TIRE WITH IMPROVED RUBBER COMPOUND BRIDGESTONE EUROPE NV SA (BE) 2026-05-27 EP disclosed
US-20260132240-A1 LINEAR BLOCK COPOLYMER AND CURABLE THERMOSETTING COMPOSITION COMPRISING THE LINEAR BLOCK COPOLYMER SHPP GLOBAL TECH B V (NL) 2026-05-14 US disclosed
EP-4349616-B1 RUBBER COMPOSITION FOR TIRE, TREAD RUBBER, AND TIRE BRIDGESTONE CORP (JP) 2026-05-06 EP disclosed
EP-4349900-B1 VULCANIZED RUBBER COMPOSITION AND TIRE BRIDGESTONE CORP (JP) 2026-04-08 EP disclosed
EP-4349901-B1 RUBBER COMPOSITION AND TIRE BRIDGESTONE CORP (JP) 2026-04-08 EP disclosed
US-20260055262-A1 RUBBER COMPOSITION FOR TIRES YOKOHAMA RUBBER CO LTD (JP) 2026-02-26 US disclosed
EP-4349614-B1 RUBBER COMPOSITION FOR TIRE, TREAD RUBBER, AND TIRE BRIDGESTONE CORP (JP) 2026-02-25 EP disclosed
EP-4349615-B1 RUBBER COMPOSITION FOR TIRE, TREAD RUBBER, AND TIRE BRIDGESTONE CORP (JP) 2026-02-18 EP disclosed
US-20260035547-A1 RUBBER COMPOSITION YOKOHAMA RUBBER CO LTD (JP) 2026-02-05 US disclosed
WO-2025262619-A1 RUBBER COMPOSITIONS BRIDGESTONE CORPORATION (JP) 2025-12-26 WO disclosed
EP-2130841-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER, AND RUBBER COMPOSITION JSR Corporation (JP) 2009-12-09 EP disclosed
EP-2098541-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER, AND RUBBER COMPOSITION JSR Corporation (JP) 2009-09-09 EP disclosed
EP-2098540-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER, AND RUBBER COMPOSITION JSR Corporation (JP) 2009-09-09 EP disclosed
EP-2098554-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER, AND RUBBER COMPOSITION JSR Corporation (JP) 2009-09-09 EP disclosed
EP-2085419-A1 PROCESS FOR PRODUCING MODIFIED POLYMER, MODIFIED POLYMER OBTAINED BY THE PROCESS, AND RUBBER COMPOSITION CONTAINING THE SAME JSR Corporation (JP) 2009-08-05 EP disclosed
EP-2075278-A1 PROCESS FOR PRODUCTION OF MODIFIED CONJUGATED DIENE POLYMERS, MODIFIED CONJUGATED DIENE POLYMERS PRODUCED BY THE PROCESS, RUBBER COMPOSITIONS, AND TIRES Bridgestone Corporation (JP) 2009-07-01 EP disclosed
EP-1932869-A1 PROCESS FOR PRODUCING MODIFIED CONJUGATED DIENE POLYMER, MODIFIED CONJUGATED DIENE POLYMER OBTAINED BY THE PROCESS, AND RUBBER COMPOSITION CONTAINING THE SAME JSR Corporation (JP) 2008-06-18 EP disclosed
US-20080103261-A1 Process for producing modified conjugated diene based polymer, modified conjugated diene based polymer produced by the process, rubber composition, and tire BRIDGESTONE CORPORATION 2008-05-01 US disclosed
US-20050070672-A1 Conjugated diene polymer, process for its production and rubber compositions containing the same BRIDGESTONE CORPORATION (JP) 2005-03-31 US disclosed
EP-1449857-A1 CONJUGATED DIENE POLYMER, PROCESS FOR ITS PRODUCTION AND RUBBER COMPOSITIONS CONTAINING THE SAME Bridgestone Corporation (JP) 2004-08-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035547-A1 RUBBER COMPOSITION LBR, TAF1, CCT4 PTGS2 267/4885ALDH1A1 1998/4885FBP1 1081/4885
US-20260055262-A1 RUBBER COMPOSITION FOR TIRES TRRAP, RAD51, TERT PTGS2 722/4885ALDH1A1 2033/4885FBP1 2282/4885
US-20260132240-A1 LINEAR BLOCK COPOLYMER AND CURABLE THERMOSETTING COMPOSITION COMPRISING THE LINEAR BLOCK COPOLYMER CBLB, UBE4A, PSMD14 PTGS2 1186/4885ALDH1A1 1440/4885FBP1 2115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.