Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.48 |
| ▸ | CTSD | P07339 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6858339 | 0.89 | CTSD (0.46) | CTSDRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL6326183 | 0.88 | RAB9A (0.50) | CTSDRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL329986 | 0.87 | RAB9A (0.47) | CTSDRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL7407867 | 0.85 | CTSD (0.57) | CTSDRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL9249682 | 0.84 | CTSD (0.53) | CTSDRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL3449783 | 0.83 | TAAR1 (0.54) | HTR2ACTSDRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7415175 | 0.83 | CTSD (0.53) | CTSDRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL9250162 | 0.82 | RAB9A (0.54) | CTSDRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL26365149 | 0.81 | SMN1; SMN2 (0.48) | CTSDRAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL23124356 | 0.80 | HTT (0.48) | SMN1; SMN2NPC1MEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004068139-A2 | IMPROVEMENT OF CATALYTIC EFFICIENCY AND/OR SPECIFICITY OF NON-NATIVE SUBSTRATES OF ENZYMES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2004-08-12 | — | — | WO | claimed |
| EP-1774033-A4 | MULTIPLEXING ASSAYS FOR ANALYTE DETECTION | PERKINELMER LAS INC (US) | 2008-04-23 | — | — | EP | disclosed |
| EP-1774033-A2 | MULTIPLEXING ASSAYS FOR ANALYTE DETECTION | PerkinElmer LAS, Inc. (US) | 2007-04-18 | — | — | EP | disclosed |
| WO-2005123959-A2 | MULTIPLEXING ASSAYS FOR ANALYTE DETECTION | PERKINELMER LAS, INC. (US) | 2005-12-29 | — | — | WO | disclosed |